Literature DB >> 17013952

Oxetanes as promising modules in drug discovery.

Georg Wuitschik1, Mark Rogers-Evans, Klaus Müller, Holger Fischer, Björn Wagner, Franz Schuler, Liudmila Polonchuk, Erick M Carreira.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 17013952     DOI： 10.1002/anie.200602343

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


× No keyword cloud information.
  24 in total

1.  An Oxetane-Based Polyketide Surrogate To Probe Substrate Binding in a Polyketide Synthase.

Authors:  Bryan D Ellis; Jacob C Milligan; Alexander R White; Vy Duong; Pilar X Altman; Lina Y Mohammed; Matthew P Crump; John Crosby; Ray Luo; Christopher D Vanderwal; Shiou-Chuan Tsai
Journal:  J Am Chem Soc       Date:  2018-04-10       Impact factor: 15.419

2.  Gold-catalyzed one-step practical synthesis of oxetan-3-ones from readily available propargylic alcohols.

Authors:  Longwu Ye; Weimin He; Liming Zhang
Journal:  J Am Chem Soc       Date:  2010-06-30       Impact factor: 15.419

Review 3.  Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.

Authors:  Shikha Kumari; Angelica V Carmona; Amit K Tiwari; Paul C Trippier
Journal:  J Med Chem       Date:  2020-08-04       Impact factor: 7.446

4.  Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group.

Authors:  Pierrik Lassalas; Killian Oukoloff; Vishruti Makani; Michael James; Van Tran; Yuemang Yao; Longchuan Huang; Krishna Vijayendran; Ludovica Monti; John Q Trojanowski; Virginia M-Y Lee; Marisa C Kozlowski; Amos B Smith; Kurt R Brunden; Carlo Ballatore
Journal:  ACS Med Chem Lett       Date:  2017-07-05       Impact factor: 4.345

5.  Metabolically Stable tert-Butyl Replacement.

Authors:  David Barnes-Seeman; Monish Jain; Leslie Bell; Suzie Ferreira; Scott Cohen; Xiao-Hui Chen; Jakal Amin; Brad Snodgrass; Panos Hatsis
Journal:  ACS Med Chem Lett       Date:  2013-04-22       Impact factor: 4.345

6.  Synthesis of 1,3-Substituted Cyclobutanes by Allenoate-Alkene [2 + 2] Cycloaddition.

Authors:  Michael L Conner; M Kevin Brown
Journal:  J Org Chem       Date:  2016-08-25       Impact factor: 4.354

7.  Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1).

Authors:  Catherine White; Meredeth A McGowan; Hua Zhou; Nunzio Sciammetta; Xavier Fradera; Jongwon Lim; Elizabeth M Joshi; Christine Andrews; Elliott B Nickbarg; Phillip Cowley; Sarah Trewick; Martin Augustin; Konstanze von Köenig; Charles A Lesburg; Karin Otte; Ian Knemeyer; Hyun Woo; Wensheng Yu; Mangeng Cheng; Peter Spacciapoli; Prasanthi Geda; Xuelei Song; Nadya Smotrov; Patrick Curran; Mee Ra Heo; Pravien Abeywickrema; J Richard Miller; David Jonathan Bennett; Yongxin Han
Journal:  ACS Med Chem Lett       Date:  2020-03-10       Impact factor: 4.345

8.  Oxetanyl Sulfoxide MMS-350 Ameliorates Pulmonary Fibrosis In Vitro, In Vivo, and Ex Vivo.

Authors:  Logan Mlakar; Jessica Lane; Takahisa Takihara; Chaemin Lim; Melissa M Sprachman; Kayla R Lloyd; Peter Wipf; Carol Feghali-Bostwick
Journal:  ACS Med Chem Lett       Date:  2020-09-10       Impact factor: 4.345

9.  Enantioselective intramolecular openings of oxetanes catalyzed by (salen)Co(III) complexes: access to enantioenriched tetrahydrofurans.

Authors:  Rebecca N Loy; Eric N Jacobsen
Journal:  J Am Chem Soc       Date:  2009-03-04       Impact factor: 15.419

Review 10.  Put a ring on it: application of small aliphatic rings in medicinal chemistry.

Authors:  Matthias R Bauer; Paolo Di Fruscia; Simon C C Lucas; Iacovos N Michaelides; Jennifer E Nelson; R Ian Storer; Benjamin C Whitehurst
Journal:  RSC Med Chem       Date:  2021-01-07
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.