Literature DB >> 17013730

Underutilization of antiosteoporotic drugs by orthopedic surgeons for prevention of a secondary osteoporotic fracture.

Kousuke Iba1, Junichi Takada, Naoko Hatakeyama, Mitsunori Kaya, Satoshi Isogai, Hajime Tsuda, Hiroyuki Obata, Suichi Miyano, Toshihiko Yamashita.   

Abstract

BACKGROUND: Despite the availability of effective treatment and well-publicized treatment guidelines for preventing osteoporotic fractures, there are significant gaps in implementing the recommendations, and it is unknown how many patients are treated for prevention of secondary osteoporotic fractures. In this study, we investigate what percentage of osteoporosis patients were treated with antiosteoporotic drugs after osteoporotic fractures of the hip, wrist, and proximal humerus, and we discuss here the need for improvement in the treatment of osteoporosis following fracture.
METHODS: We studied 422 patients with osteoporotic fractures, 91 men and 331 women, with an average age of 77.1 years (range, 52-102 years). The 422 cases consisted of 299 hip fractures, 97 distal radius fractures, and 26 proximal humerus fractures. All patients underwent surgical intervention. The variables were examined to ascertain whether osteoporosis patients were medicated with antiosteoporotic drugs at postfracture.
RESULTS: Fifty-five (13%) of the 422 patients received antiosteoporotic medication at postfracture. Pharmaceutical treatment was given in 44 cases (14.7%) of hip fractures, 8 cases (8.2%) of distal radius fractures, and 3 cases (11.5%) of proximal humerus fractures. Thirty-one (7.3% of total) of the 55 patients were taking the same medication pre- and postfracture. Seven (1.7%) of the 55 were administered a different drug compared to before the fracture, and 17 (4%) started to take an antiosteoporotic drug for the first time subsequent to the fracture.
CONCLUSIONS: The present rate of treatment is insufficient given the high risk of secondary fractures and the availability of appropriate drugs that would reduce that risk.

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Year:  2006        PMID: 17013730     DOI: 10.1007/s00776-006-1050-9

Source DB:  PubMed          Journal:  J Orthop Sci        ISSN: 0949-2658            Impact factor:   1.601


  8 in total

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2.  Inadequate management for secondary fracture prevention in patients with distal radius fracture by trauma surgeons.

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Journal:  Clin Drug Investig       Date:  2007       Impact factor: 2.859

Review 4.  What is the best balance of benefits and risks among anti-resorptive therapies for postmenopausal osteoporosis?

Authors:  P D Miller; R J Derman
Journal:  Osteoporos Int       Date:  2010-03-23       Impact factor: 4.507

Review 5.  Osteoporosis and treatments in Japan: management for preventing subsequent fractures.

Authors:  Shuko Nojiri; Russel T Burge; Jennifer A Flynn; Shonda A Foster; Hideaki Sowa
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6.  The utility and limitations of FRAX: A US perspective.

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Review 7.  Systematic review of raloxifene in postmenopausal Japanese women with osteoporosis or low bone mass (osteopenia).

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Journal:  Clin Interv Aging       Date:  2014-11-05       Impact factor: 4.458

8.  Healthcare Policy Changes in Osteoporosis Can Improve Outcomes and Reduce Costs in the United States.

Authors:  E Michael Lewiecki; Jesse D Ortendahl; Jacqueline Vanderpuye-Orgle; Andreas Grauer; Jorge Arellano; Jeffrey Lemay; Amanda L Harmon; Michael S Broder; Andrea J Singer
Journal:  JBMR Plus       Date:  2019-05-13
  8 in total

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