Literature DB >> 17013584

[Guidelines given by the DSG and DGN concerning stroke therapy--new therapeutic aspects].

M Grond1.   

Abstract

Surgeries of symptomatic carotid stenose should not be operated on later than 14 days after stroke; until the operation inhibitors of platelet aggregation have to be administered (Table 1). The application of anticoagulants like warfarin or phenprocoumon in case of intracranial stenoses is no longer recommended. Instead 100-300 mg aspirin should prophylactically be given. The risk of suffering a stroke is significantly reduced by the application of antihypertensives. Patients with focal cerebral ischemia should be given 40 mg of Simvastatin which leads to a significant decrease of vascular risk. After the first cerebral ischemic incidenz patients with open foramen ovale of the heart should be given 100-300 mg aspirin. In case of aspirin relapse an oral anticoagulation has to be carried out with an INR of 2.0 up to 3 for at least one year.

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Year:  2006        PMID: 17013584     DOI: 10.1007/s00392-006-1808-2

Source DB:  PubMed          Journal:  Clin Res Cardiol        ISSN: 1861-0684            Impact factor:   5.460


  8 in total

1.  European Stroke Prevention Study 2. Efficacy and safety data.

Authors: 
Journal:  J Neurol Sci       Date:  1997-09       Impact factor: 3.181

2.  Efficacy of aspirin plus extended-release dipyridamole in preventing recurrent stroke in high-risk populations.

Authors:  Ralph L Sacco; Juhani Sivenius; Hans-Christoph Diener
Journal:  Arch Neurol       Date:  2005-03

3.  Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis.

Authors:  Marc I Chimowitz; Michael J Lynn; Harriet Howlett-Smith; Barney J Stern; Vicki S Hertzberg; Michael R Frankel; Steven R Levine; Seemant Chaturvedi; Scott E Kasner; Curtis G Benesch; Cathy A Sila; Tudor G Jovin; Jose G Romano
Journal:  N Engl J Med       Date:  2005-03-31       Impact factor: 91.245

4.  Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES).

Authors:  Joachim Schrader; Stephan Lüders; Anke Kulschewski; Frank Hammersen; Kerstin Plate; Jürgen Berger; Walter Zidek; Peter Dominiak; Hans Christoph Diener
Journal:  Stroke       Date:  2005-05-05       Impact factor: 7.914

5.  Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack.

Authors: 
Journal:  Lancet       Date:  2001-09-29       Impact factor: 79.321

6.  Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial.

Authors:  Hans-Christoph Diener; Julien Bogousslavsky; Lawrence M Brass; Claudio Cimminiello; Laszlo Csiba; Markku Kaste; Didier Leys; Jordi Matias-Guiu; Hans-Jürgen Rupprecht
Journal:  Lancet       Date:  2004 Jul 24-30       Impact factor: 79.321

7.  Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions.

Authors:  Rory Collins; Jane Armitage; Sarah Parish; Peter Sleight; Richard Peto
Journal:  Lancet       Date:  2004-03-06       Impact factor: 79.321

8.  Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery.

Authors:  P M Rothwell; M Eliasziw; S A Gutnikov; C P Warlow; H J M Barnett
Journal:  Lancet       Date:  2004-03-20       Impact factor: 79.321

  8 in total

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