Literature DB >> 1701273

Detection of a human intracisternal A-type retroviral particle antigenically related to HIV.

R F Garry1, C D Fermin, D J Hart, S S Alexander, L A Donehower, H Luo-Zhang.   

Abstract

Sjögren's syndrome is an autoimmune disease that is characterized by dryness of the mouth and eyes. The loss of salivary and lacrimal gland function is accompanied by lymphocytic infiltration. Because similar symptoms and glandular pathology are observed in certain persons infected with human immunodeficiency virus (HIV), a search was initiated for a possible retroviral etiology in this syndrome. A human intracisternal A-type retroviral particle that is antigenically related to HIV was detected in lymphoblastoid cells exposed to homogenates of salivary tissue from patients with Sjögren's syndrome. Comparison of this retroviral particle to HIV indicates that they are distinguishable by several ultrastructural, physical, and enzymatic criteria.

Entities:  

Keywords:  NASA Discipline Neuroscience; Non-NASA Center

Mesh：

Substances：

Year:  1990        PMID： 1701273     DOI： 10.1126/science.1701273

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  46 in total

1.  Possible involvement of IL-12 expression by Epstein-Barr virus in Sjögren syndrome.

Authors:  M Horiuchi; S Yamano; H Inoue; J Ishii; Y Nagata; H Adachi; M Ono; J N Renard; F Mizuno; Y Hayashi; I Saito
Journal:  J Clin Pathol       Date:  1999-11       Impact factor: 3.411

2.  CD4 cytotoxic and dendritic cells in the immunopathologic lesion of Sjögren's syndrome.

Authors:  G Xanthou; N I Tapinos; M Polihronis; I P Nezis; L H Margaritis; H M Moutsopoulos
Journal:  Clin Exp Immunol       Date:  1999-10       Impact factor: 4.330

3.  Primary Sjögren's syndrome with antibodies to HTLV-I: clinical and laboratory features.

Authors:  K Eguchi; N Matsuoka; H Ida; M Nakashima; M Sakai; S Sakito; A Kawakami; K Terada; H Shimada; Y Kawabe
Journal:  Ann Rheum Dis       Date:  1992-06       Impact factor: 19.103

Review 4.  Infectious diseases and AIDS.

Authors:  P D Welsby
Journal:  Postgrad Med J       Date:  1992-06       Impact factor: 2.401

Review 5.  Slow viruses and the immune system in the pathogenesis of local tissue damage in Sjögren's syndrome.

Authors:  G K Papadopoulos; H M Moutsopoulos
Journal:  Ann Rheum Dis       Date:  1992-01       Impact factor: 19.103

Review 6.  Systemic lupus erythematosus: RNA-protein autoantigens, models of disease heterogeneity, and theories of etiology.

Authors:  J B Harley; R H Scofield
Journal:  J Clin Immunol       Date:  1991-11       Impact factor: 8.317

Review 7.  Persistent viral infection in primary Sjogren's syndrome: review and perspectives.

Authors:  Antigoni Triantafyllopoulou; Haralampos Moutsopoulos
Journal:  Clin Rev Allergy Immunol       Date:  2007-06       Impact factor: 8.667

8.  Frequencies of HIV-reactive B cells in seropositive and seronegative individuals.

Authors:  R H Zubler; L H Perrin; A Doucet; X Zhang; Y P Huang; P A Miescher
Journal:  Clin Exp Immunol       Date:  1992-01       Impact factor: 4.330

9.  Isolation of a C-type retrovirus from an HIV infected cell line.

Authors:  G Burtonboy; N Delferriere; B Mousset; M Heusterspreute
Journal:  Arch Virol       Date:  1993       Impact factor: 2.574

10.  Increased epithelial expression of HLA-DQ and HLA-DP molecules in salivary glands from patients with Sjögren's syndrome compared with obstructive sialadenitis.

Authors:  P S Thrane; T S Halstensen; H R Haanaes; P Brandtzaeg
Journal:  Clin Exp Immunol       Date:  1993-05       Impact factor: 4.330
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