Literature DB >> 17010825

Outcomes of antipsychotic drug use in community-dwelling elders with dementia.

Ann Kolanowski1, Donna Fick, Jennifer L Waller, Frank Ahern.   

Abstract

This study used administrative data from a large health care insurer in the southeast United States to describe the utilization pattern and health care outcomes of antipsychotic drug use in community-dwelling elders with dementia. Claims data from 959 unique cases were analyzed to address research aims. Overall, 27% of the sample was dispensed antipsychotic drugs, with the most prevalent type being atypical antipsychotic drugs. Individuals on any type of antipsychotic drug experienced more delirium, depression, hip fracture, falls, and syncope than those not on these drugs, even after controlling for age, sex, comorbidity, and number of other drugs prescribed. Implications for practice are discussed.

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Year:  2006        PMID: 17010825     DOI: 10.1016/j.apnu.2006.04.004

Source DB:  PubMed          Journal:  Arch Psychiatr Nurs        ISSN: 0883-9417            Impact factor:   2.218


  24 in total

1.  Risk of hospitalization for stroke associated with antipsychotic use in the elderly: a self-controlled case series.

Authors:  Nicole L Pratt; Elizabeth E Roughead; Emmae Ramsay; Amy Salter; Philip Ryan
Journal:  Drugs Aging       Date:  2010-11-01       Impact factor: 3.923

2.  Behavioral disturbance in dementia.

Authors:  Abhilash K Desai; Lori Schwartz; George T Grossberg
Journal:  Curr Psychiatry Rep       Date:  2012-08       Impact factor: 5.285

Review 3.  Use of antipsychotics increases the risk of fracture: a systematic review and meta-analysis.

Authors:  S-H Lee; W-T Hsu; C-C Lai; A Esmaily-Fard; Y-W Tsai; C-C Chiu; J Wang; S-S Chang; C C Lee
Journal:  Osteoporos Int       Date:  2017-01-12       Impact factor: 4.507

4.  Health outcomes associated with potentially inappropriate medication use in older adults.

Authors:  Donna M Fick; Lorraine C Mion; Mark H Beers; Jennifer L Waller
Journal:  Res Nurs Health       Date:  2008-02       Impact factor: 2.228

5.  Aggression in persons with dementia: use of nursing theory to guide clinical practice.

Authors:  Diane Dettmore; Ann Kolanowski; Malaz Boustani
Journal:  Geriatr Nurs       Date:  2009 Jan-Feb       Impact factor: 2.361

Review 6.  Are the safety profiles of antipsychotic drugs used in dementia the same? An updated review of observational studies.

Authors:  Gianluca Trifiró; Janet Sultana; Edoardo Spina
Journal:  Drug Saf       Date:  2014-07       Impact factor: 5.606

7.  Risk of hospitalization for hip fracture and pneumonia associated with antipsychotic prescribing in the elderly: a self-controlled case-series analysis in an Australian health care claims database.

Authors:  Nicole Pratt; Elizabeth E Roughead; Emmae Ramsay; Amy Salter; Philip Ryan
Journal:  Drug Saf       Date:  2011-07-01       Impact factor: 5.606

8.  Good Intentions, But What About Unintended Consequences?

Authors:  Helen C Kales; Donovan T Maust
Journal:  Drug Saf       Date:  2017-08       Impact factor: 5.606

9.  Association of the Centers for Medicare & Medicaid Services' National Partnership to Improve Dementia Care With the Use of Antipsychotics and Other Psychotropics in Long-term Care in the United States From 2009 to 2014.

Authors:  Donovan T Maust; H Myra Kim; Claire Chiang; Helen C Kales
Journal:  JAMA Intern Med       Date:  2018-05-01       Impact factor: 21.873

10.  Documentation of antipsychotic use and indications for newly diagnosed, nonaggressive dementia patients.

Authors:  Nikhil Dhawan; Avila B Steele; Robert O Morgan; A Lynn Snow; Jessica A Davila; Mark E Kunik
Journal:  Prim Care Companion J Clin Psychiatry       Date:  2008
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