Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Lassa virus glycoproteins: antigenic and immunogenic properties of synthetic peptides to GP1.

Literature DB >> 1701079

Lassa virus glycoproteins: antigenic and immunogenic properties of synthetic peptides to GP1.

A G Krasko¹, A B Moshnikova, A T Kozhich, L D Tchikin, V T Ivanov, A S Vladyko, I S Lukashevich.

Abstract

Synthetic peptides corresponding to predicted Lassa virus GP1 glycoprotein B-epitopes were used to study the antigenicity and immunogenicity of the protein. ELISA results showed that guinea pig polyclonal anti-Lassa virus serum bound effectively to peptides corresponding to amino acid residues 119-133 and 164-176 of the GP1 protein. Essentially it did not react to a peptide corresponding to GP1 amino acid residues 234-256. Sera obtained against peptides representing amino acid residues 119-133 and 164-176 reacted with inactivated purified Lassa virus.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1990 PMID： 1701079 DOI： 10.1007/bf01310630

Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574

11 in total

7. Nucleotide sequence of the Lassa virus (Josiah strain) S genome RNA and amino acid sequence comparison of the N and GPC proteins to other arenaviruses.

Authors: D D Auperin; J B McCormick
Journal: Virology Date: 1989-02 Impact factor: 3.616

2. Benchmarking B-cell epitope prediction with quantitative dose-response data on antipeptide antibodies: towards novel pharmaceutical product development.

Authors: Salvador Eugenio C Caoili
Journal: Biomed Res Int Date: 2014-05-11 Impact factor: 3.411

2 in total

Lassa virus glycoproteins: antigenic and immunogenic properties of synthetic peptides to GP1.

Review 1. Arenavirus gene structure and organization.

Review 2. Production and use of antibodies against synthetic peptides.

3. Proteins of lymphocytic choriomeningitis virus: antigenic topography of the viral glycoproteins.

4. Nucleotide sequence of the glycoprotein gene and intergenic region of the Lassa virus S genome RNA.

5. Evolutionary biology of a Lassa virus complex.

6. Prediction of protein antigenic determinants from amino acid sequences.

7. Nucleotide sequence of the Lassa virus (Josiah strain) S genome RNA and amino acid sequence comparison of the N and GPC proteins to other arenaviruses.

8. Lassa fever, a new virus disease of man from West Africa. 3. Isolation and characterization of the virus.

9. Protection of Lassa virus-infected guinea pigs with Lassa-immune plasma of guinea pig, primate, and human origin.

10. Fine mapping of a peptide sequence containing an antigenic site conserved among arenaviruses.

1. Imported lassa fever in Germany: molecular characterization of a new lassa virus strain.

2. Benchmarking B-cell epitope prediction with quantitative dose-response data on antipeptide antibodies: towards novel pharmaceutical product development.