Literature DB >> 17008045

Protein modification in aging: an update.

Christian Schöneich1.   

Abstract

Post-translational modifications of proteins are an important biologic tool for the production of various protein species from a single gene, which may vary in conformation, function, biologic half-life and complex formation with other proteins. The present minireview summarizes a few selected research observations important for the role of post-translational modifications in biologic aging and age-related diseases, including farnesylation, methylglyoxal-derivatization, transglutaminase pathways and the formation of 3-nitrotyrosine and 2-oxo-histidine in vivo.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 17008045     DOI： 10.1016/j.exger.2006.07.002

Source DB:  PubMed          Journal:  Exp Gerontol        ISSN： 0531-5565            Impact factor:   4.032


  17 in total

Review 1.  p53, oxidative stress, and aging.

Authors:  Dongping Liu; Yang Xu
Journal:  Antioxid Redox Signal       Date:  2011-02-07       Impact factor: 8.401

2.  Ubiquitin proteasome pathway-mediated degradation of proteins: effects due to site-specific substrate deamidation.

Authors:  Edward J Dudek; Kirsten J Lampi; Jason A Lampi; Fu Shang; Jonathan King; Yongting Wang; Allen Taylor
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-06-30       Impact factor: 4.799

3.  Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression.

Authors:  J Julie Wu; Jie Liu; Edmund B Chen; Jennifer J Wang; Liu Cao; Nisha Narayan; Marie M Fergusson; Ilsa I Rovira; Michele Allen; Danielle A Springer; Cory U Lago; Shuling Zhang; Wendy DuBois; Theresa Ward; Rafael deCabo; Oksana Gavrilova; Beverly Mock; Toren Finkel
Journal:  Cell Rep       Date:  2013-08-29       Impact factor: 9.423

Review 4.  Protein oxidative modifications in the ageing brain: consequence for the onset of neurodegenerative disease.

Authors:  Stefanie Grimm; Annika Hoehn; Kelvin J Davies; Tilman Grune
Journal:  Free Radic Res       Date:  2010-09-06

5.  Detection and quantitation of succinimide in intact protein via hydrazine trapping and chemical derivatization.

Authors:  Joshua J Klaene; Wenqin Ni; Joshua F Alfaro; Zhaohui Sunny Zhou
Journal:  J Pharm Sci       Date:  2014-07-14       Impact factor: 3.534

6.  Effect of progerin on the accumulation of oxidized proteins in fibroblasts from Hutchinson Gilford progeria patients.

Authors:  Gabriela Viteri; Youn Wook Chung; Earl R Stadtman
Journal:  Mech Ageing Dev       Date:  2009-12-01       Impact factor: 5.432

Review 7.  Studies of complex biological systems with applications to molecular medicine: the need to integrate transcriptomic and proteomic approaches.

Authors:  Elena Silvestri; Assunta Lombardi; Pieter de Lange; Daniela Glinni; Rosalba Senese; Federica Cioffi; Antonia Lanni; Fernando Goglia; Maria Moreno
Journal:  J Biomed Biotechnol       Date:  2010-10-11

Review 8.  A mother's sacrifice: what is she keeping for herself?

Authors:  Kiersten A Henderson; Daniel E Gottschling
Journal:  Curr Opin Cell Biol       Date:  2008-10-23       Impact factor: 8.382

9.  Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection.

Authors:  Sean M Sliman; Timothy D Eubank; Sainath R Kotha; M Lakshmi Kuppusamy; Shariq I Sherwani; Elizabeth Susan O'Connor Butler; Periannan Kuppusamy; Sashwati Roy; Clay B Marsh; David M Stern; Narasimham L Parinandi
Journal:  Mol Cell Biochem       Date:  2009-07-08       Impact factor: 3.396

10.  Age-related reduction in retinal deimination levels in the F344BN rat.

Authors:  Sanjoy K Bhattacharya; Brent Sinicrope; Mary E Rayborn; Joe G Hollyfield; Vera L Bonilha
Journal:  Aging Cell       Date:  2008-01-31       Impact factor: 9.304
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.