Literature DB >> 17005829

Reactivity of (1-->3)-beta-d-glucan assay with commonly used intravenous antimicrobials.

Francisco M Marty1, Colleen M Lowry, Steven J Lempitski, David W Kubiak, Malcolm A Finkelman, Lindsey R Baden.   

Abstract

Forty-four intravenous antimicrobials were tested for the presence of (1-->3)-beta-d-glucan (BG). Colistin, ertapenem, cefazolin, trimethoprim-sulfamethoxazole, cefotaxime, cefepime, and ampicillin-sulbactam tested positive for BG at reconstituted-vial concentrations but not when diluted to usual maximum plasma concentrations. False-positive BG assays may occur when some antimicrobials are administered; however, this needs to be confirmed.

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Year:  2006        PMID: 17005829      PMCID: PMC1610103          DOI: 10.1128/AAC.00658-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  16 in total

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5.  Positive (1-->3)-beta-D-glucan in blood components and release of (1-->3)-beta-D-glucan from depth-type membrane filters for blood processing.

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