Literature DB >> 17005090

Progress in researches on the pharmaceutical mechanism and clinical application of Ginkgo Biloba extract on various kinds of diseases.

Guo-xia Wang1, Fu-liang Cao, Jun Chen.   

Abstract

Progress made over the pharmaceutical mechanism and clinical application of Ginkgo Biloba extract (GBE) on various kinds of diseases were reviewed in this paper. The effective elements contained in GBE are mainly kinds of Ginkgo flavonoid and Ginkgolide, which have marked protective effects on cardio-cerebral vascular and central nerve systems. In clinical practice, it is applied mostly in treatment of cardio-cerebral vascular diseases. Also it shows apparent effects in the treatment processes of some other diseases as an adjuvant, and therefore, has been gradually accepted by the medical circle in the world, proving to be a medicine of wide prospect in development and application.

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Year:  2006        PMID： 17005090     DOI： 10.1007/bf02836532

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN： 1672-0415            Impact factor:   1.978


  13 in total

1.  A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group.

Authors:  P L Le Bars; M M Katz; N Berman; T M Itil; A M Freedman; A F Schatzberg
Journal:  JAMA       Date:  1997 Oct 22-29       Impact factor: 56.272

2.  [Effects of Ginkgo biloba extract on number and activity of endothelial progenitor cells from peripheral blood].

Authors:  Xing-xiang Wang; Yun-peng Shang; Jun-zhu Chen; Jun-hui Zhu; Xiao-gang Guo; Jian Sun
Journal:  Yao Xue Xue Bao       Date:  2004-08

3.  [Experimental studies of the protective effect of ginkgo biloba extract (GBE) on cisplatin-induced toxicity in rats].

Authors:  H Fukaya; H Kanno
Journal:  Nihon Jibiinkoka Gakkai Kaiho       Date:  1999-07

4.  Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions.

Authors:  C La Casa; I Villegas; C Alarcón de la Lastra; V Motilva; M J Martín Calero
Journal:  J Ethnopharmacol       Date:  2000-07       Impact factor: 4.360

5.  Molecular and cellular assessment of ginkgo biloba extract as a possible ophthalmic drug.

Authors:  Geetha Thiagarajan; Sushil Chandani; Sithamraju Harinarayana Rao; Ayelet M Samuni; Krish Chandrasekaran; Dorairajan Balasubramanian
Journal:  Exp Eye Res       Date:  2002-10       Impact factor: 3.467

6.  Application of antioxidants and other agents to prevent cisplatin ototoxicity.

Authors:  L P Rybak; C Whitworth; S Somani
Journal:  Laryngoscope       Date:  1999-11       Impact factor: 3.325

7.  Bcl-x(L) forms an ion channel in synthetic lipid membranes.

Authors:  A J Minn; P Vélez; S L Schendel; H Liang; S W Muchmore; S W Fesik; M Fill; C B Thompson
Journal:  Nature       Date:  1997-01-23       Impact factor: 49.962

8.  Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction.

Authors:  J Misao; Y Hayakawa; M Ohno; S Kato; T Fujiwara; H Fujiwara
Journal:  Circulation       Date:  1996-10-01       Impact factor: 29.690

Review 9.  Liver disease in alcohol abusers: clinical perspective.

Authors:  Anna Mae Diehl
Journal:  Alcohol       Date:  2002-05       Impact factor: 2.405

10.  Therapeutic efficacy of EGb761 (Gingko biloba extract) in a transgenic mouse model of amyotrophic lateral sclerosis.

Authors:  R J Ferrante; A M Klein; A Dedeoglu; M F Beal
Journal:  J Mol Neurosci       Date:  2001-08       Impact factor: 2.866
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  4 in total

1.  The change of the spinal cord ischemia-reperfusion injury in mitochondrial passway and the effect of the Ginkgo biloba extract's preconditioning intervention.

Authors:  Bin Cheng; Weizhuo Wang; Lei Lin; Fengtao Li; Xin Wang
Journal:  Cell Mol Neurobiol       Date:  2010-12-10       Impact factor: 5.046

2.  Protective effect of ginkgolide B against acute spinal cord injury in rats and its correlation with the Jak/STAT signaling pathway.

Authors:  Yongxing Song; Zhongyou Zeng; Caiyi Jin; Jianqiao Zhang; Baoyue Ding; Feng Zhang
Journal:  Neurochem Res       Date:  2012-12-29       Impact factor: 3.996

Review 3.  Antioxidative Effects of Natural Products on Diabetic Cardiomyopathy.

Authors:  Bingdi Yan; Jin Ren; Qinghua Zhang; Rong Gao; Fenglian Zhao; Junduo Wu; Junling Yang
Journal:  J Diabetes Res       Date:  2017-10-18       Impact factor: 4.011

4.  Efficacy and Safety of Ginkgo Biloba Pills for Coronary Heart Disease with Impaired Glucose Regulation: Study Protocol for a Series of N-of-1 Randomized, Double-Blind, Placebo-Controlled Trials.

Authors:  Mingyue Sun; Lulu Chai; Fang Lu; Yang Zhao; Qingna Li; Boya Cui; Rui Gao; Yue Liu
Journal:  Evid Based Complement Alternat Med       Date:  2018-10-14       Impact factor: 2.629
  4 in total

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