BACKGROUND: Calls for increased investment in sexually transmitted infection (STI) treatment across the developing world have been made to address the high disease burden and the association with HIV transmission. GOALS: The goals of this study were to systematically review evidence on the cost of treating curable STIs and to explore its key determinants. STUDY: A search of published literature was conducted in PubMed and supplemented by reviews of gray literature. Studies were analyzed by broad focus. Regression analysis explored how intervention characteristics affect unit costs, accounting for differences in costing methods. RESULTS: Fifty-three primary studies were identified, of which 62% used empirical data, 35% presented economic costs, and 22% presented full costs. The median STI treatment cost was US dollars 17.80. Clinics serving symptomatic patients were consistently cheaper than outreach services, services using syndromic management protocols had lower costs, and unit costs decreased with scale. CONCLUSIONS: The compiled cost data provide an evidence base that can be used to help inform resource planning.
BACKGROUND: Calls for increased investment in sexually transmitted infection (STI) treatment across the developing world have been made to address the high disease burden and the association with HIV transmission. GOALS: The goals of this study were to systematically review evidence on the cost of treating curable STIs and to explore its key determinants. STUDY: A search of published literature was conducted in PubMed and supplemented by reviews of gray literature. Studies were analyzed by broad focus. Regression analysis explored how intervention characteristics affect unit costs, accounting for differences in costing methods. RESULTS: Fifty-three primary studies were identified, of which 62% used empirical data, 35% presented economic costs, and 22% presented full costs. The median STI treatment cost was US dollars 17.80. Clinics serving symptomatic patients were consistently cheaper than outreach services, services using syndromic management protocols had lower costs, and unit costs decreased with scale. CONCLUSIONS: The compiled cost data provide an evidence base that can be used to help inform resource planning.
Authors: Ângela S Inácio; Katia A Mesquita; Marta Baptista; João Ramalho-Santos; Winchil L C Vaz; Otília V Vieira Journal: PLoS One Date: 2011-05-16 Impact factor: 3.240
Authors: S Chandrashekar; L Guinness; L Kumaranayake; Bhaskar Reddy; Y Govindraj; P Vickerman; M Alary Journal: Sex Transm Infect Date: 2010-02 Impact factor: 3.519
Authors: Brooke E Nichols; Sarah J Girdwood; Thomas Crompton; Lynsey Stewart-Isherwood; Leigh Berrie; Dorman Chimhamhiwa; Crispin Moyo; John Kuehnle; Wendy Stevens; Sydney Rosen Journal: J Int AIDS Soc Date: 2019-09 Impact factor: 5.396
Authors: Navin Kumar; Laura Forastiere; Tiange Zhang; Fan Yang; Katherine T Li; Weiming Tang; Joseph D Tucker; Nicholas A Christakis; Marcus Alexander Journal: BMC Public Health Date: 2020-05-04 Impact factor: 3.295
Authors: Richard G White; Kate K Orroth; Judith R Glynn; Esther E Freeman; Roel Bakker; J Dik F Habbema; Fern Terris-Prestholt; Lilani Kumaranayake; Anne Buvé; Richard J Hayes Journal: J Acquir Immune Defic Syndr Date: 2008-03-01 Impact factor: 3.731