Literature DB >> 17002348

Stereoselective synthesis of functionalized pyrrolidines via a [3 + 2]-annulation of N-Ts-alpha-amino aldehydes and 1,3-Bis(silyl)propenes.

Per Restorp1, Andreas Fischer, Peter Somfai.   

Abstract

An efficient protocol for stereoselective synthesis of densely functionalized pyrrolidines by a [3 + 2]-annulation of N-Ts-alpha-amino aldehydes and 1,3-bis(silyl)propenes is described.

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Year:  2006        PMID: 17002348     DOI: 10.1021/ja0647102

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  4 in total

1.  Enantioselective construction of pyrrolidines by palladium-catalyzed asymmetric [3 + 2] cycloaddition of trimethylenemethane with imines.

Authors:  Barry M Trost; Steven M Silverman
Journal:  J Am Chem Soc       Date:  2012-03-02       Impact factor: 15.419

2.  Preparation of allyl and vinyl silanes by the palladium-catalyzed silylation of terminal olefins: a silyl-Heck reaction.

Authors:  Jesse R McAtee; Sara E S Martin; Derek T Ahneman; Keywan A Johnson; Donald A Watson
Journal:  Angew Chem Int Ed Engl       Date:  2012-03-01       Impact factor: 15.336

3.  Iridium-catalyzed anti-diastereo- and enantioselective carbonyl (trimethylsilyl)allylation from the alcohol or aldehyde oxidation level.

Authors:  Soo Bong Han; Xin Gao; Michael J Krische
Journal:  J Am Chem Soc       Date:  2010-07-07       Impact factor: 15.419

4.  Annulations of enantioenriched allenylsilanes with in situ generated iminium ions: stereoselective synthesis of diverse heterocycles.

Authors:  Ryan A Brawn; James S Panek
Journal:  Org Lett       Date:  2009-01-15       Impact factor: 6.005

  4 in total

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