Literature DB >> 17001013

Hormonal activity of AIMP1/p43 for glucose homeostasis.

Sang Gyu Park1, Young Sun Kang, Jin Young Kim, Chang Seok Lee, Young Gyu Ko, Woo Je Lee, Ki-Up Lee, Young Il Yeom, Sunghoon Kim.   

Abstract

AIMP1/p43 is known as a cytokine working in the control of angiogenesis, inflammation, and wound healing. Here we report its enrichment in pancreatic alpha cells and glucagon-like hormonal activity. AIMP1 is secreted from the pancreas upon glucose starvation. Exogenous infusion of AIMP1 increased plasma levels of glucose, glucagon, and fatty acid, and AIMP1-deficient mice showed reduced plasma glucose levels compared with the wild-type mice under fasting conditions. Thus, AIMP1 plays a glucagon-like role in glucose homeostasis.

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Year:  2006        PMID： 17001013      PMCID： PMC1595450          DOI： 10.1073/pnas.0602045103

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  33 in total

1.  Modification of the protein A-gold immunocytochemical technique for the enhancement of its efficiency.

Authors:  M Bendayan; M A Duhr
Journal:  J Histochem Cytochem       Date:  1986-05       Impact factor: 2.479

Review 2.  Glucagon and regulation of glucose metabolism.

Authors:  Guoqiang Jiang; Bei B Zhang
Journal:  Am J Physiol Endocrinol Metab       Date:  2003-04       Impact factor: 4.310

Review 3.  High molecular weight complexes of eukaryotic aminoacyl-tRNA synthetases.

Authors:  C V Dang; D C Yang
Journal:  Int J Biochem       Date:  1982

4.  Multienzyme complexes of mammalian aminoacyl-tRNA synthetases.

Authors:  D C Yang; J V Garcia; Y D Johnson; S Wahab
Journal:  Curr Top Cell Regul       Date:  1985

Review 5.  [Immunochemical study of tryptophanyl-tRNA-synthetase].

Authors:  S F Beresten'; V V Filonenko; O O Favorova
Journal:  Biokhimiia       Date:  1991-07

6.  Molecular and cellular studies of tryptophanyl-tRNA synthetases using monoclonal antibodies. Remarkable variations in the content of tryptophanyl-tRNA synthetase in the pancreas of different mammals.

Authors:  O O Favorova; T A Zargarova; V S Rukosuyev; S F Beresten; L L Kisselev
Journal:  Eur J Biochem       Date:  1989-10-01

7.  Norepinephrine inhibits islet lipid metabolism, 45Ca2+ uptake, and insulin secretion.

Authors:  E Vara; J Tamarit-Rodriguez
Journal:  Am J Physiol       Date:  1989-12

8.  Unlabeled antibody methods in electron microscopy: a comparison of single and multistep procedures using colloidal gold.

Authors:  E J Gosselin; G D Sorenson; J C Dennett; C C Cate
Journal:  J Histochem Cytochem       Date:  1984-08       Impact factor: 2.479

9.  Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects.

Authors:  Victoria Rotter; Ivan Nagaev; Ulf Smith
Journal:  J Biol Chem       Date:  2003-09-02       Impact factor: 5.157

10.  Seven mammalian aminoacyl-tRNA synthetases co-purified as high molecular weight entities are associated within the same complex.

Authors:  M Mirande; Y Gache; D Le Corre; J P Waller
Journal:  EMBO J       Date:  1982       Impact factor: 11.598
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  22 in total

1.  Tryptophanyl-tRNA Synthetase, a Novel Damage-Induced Cytokine, Significantly Increases the Therapeutic Effects of Endometrial Stem Cells.

Authors:  Se-Ra Park; Soo-Rim Kim; Jae-Been Im; Soyi Lim; In-Sun Hong
Journal:  Mol Ther       Date:  2020-06-19       Impact factor: 11.454

2.  The N terminus of pro-endothelial monocyte-activating polypeptide II (EMAP II) regulates its binding with the C terminus, arginyl-tRNA synthetase, and neurofilament light protein.

Authors:  Haiming Xu; Nikolay L Malinin; Niranjan Awasthi; Roderich E Schwarz; Margaret A Schwarz
Journal:  J Biol Chem       Date:  2015-02-27       Impact factor: 5.157

Review 3.  Aminoacyl tRNA synthetases and their connections to disease.

Authors:  Sang Gyu Park; Paul Schimmel; Sunghoon Kim
Journal:  Proc Natl Acad Sci U S A       Date:  2008-08-05       Impact factor: 11.205

4.  Anthocyanin inhibits high glucose-induced hepatic mtGPAT1 activation and prevents fatty acid synthesis through PKCζ.

Authors:  Honghui Guo; Dan Li; Wenhua Ling; Xiang Feng; Min Xia
Journal:  J Lipid Res       Date:  2011-02-22       Impact factor: 5.922

5.  Enhancement of toll-like receptor 2-mediated immune responses by AIMP1, a novel cytokine, in mouse dendritic cells.

Authors:  Eugene Kim; Hye-Jin Hong; Daeho Cho; Jung Min Han; Sunghoon Kim; Tae Sung Kim
Journal:  Immunology       Date:  2011-06-29       Impact factor: 7.397

6.  A novel endogenous damage signal, glycyl tRNA synthetase, activates multiple beneficial functions of mesenchymal stem cells.

Authors:  Se-Ra Park; Hyun-Jin Kim; Se-Ran Yang; Chan Hum Park; Hwa-Yong Lee; In-Sun Hong
Journal:  Cell Death Differ       Date:  2018-04-17       Impact factor: 15.828

7.  AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53.

Authors:  Jung Min Han; Bum-Joon Park; Sang Gyu Park; Young Sun Oh; So Jung Choi; Sang Won Lee; Soon-Kyung Hwang; Seung-Hee Chang; Myung-Haing Cho; Sunghoon Kim
Journal:  Proc Natl Acad Sci U S A       Date:  2008-08-11       Impact factor: 11.205

8.  ARS-interacting multi-functional protein 1 induces proliferation of human bone marrow-derived mesenchymal stem cells by accumulation of β-catenin via fibroblast growth factor receptor 2-mediated activation of Akt.

Authors:  Seo Yoon Kim; Woo Sung Son; Min Chul Park; Chul Min Kim; Byung Hyun Cha; Kang Jun Yoon; Soo-Hong Lee; Sang Gyu Park
Journal:  Stem Cells Dev       Date:  2013-06-25       Impact factor: 3.272

9.  MSC p43 required for axonal development in motor neurons.

Authors:  Xiaodong Zhu; Yang Liu; Yanqing Yin; Aiyun Shao; Bo Zhang; Sunghoon Kim; Jiawei Zhou
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-26       Impact factor: 11.205

10.  A DNA adjuvant encoding a fusion protein between anti-CD3 single-chain Fv and AIMP1 enhances T helper type 1 cell-mediated immune responses in antigen-sensitized mice.

Authors:  Byeong Cheol Lee; Insug O'Sullivan; Eugene Kim; Sang Gyu Park; Seung Yong Hwang; Daeho Cho; Tae Sung Kim
Journal:  Immunology       Date:  2008-06-10       Impact factor: 7.397
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