Literature DB >> 17000728

Borrelia burgdorferi complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes is expressed in humans and induces antibody responses restricted to nondenatured structural determinants.

Evelyn Rossmann1, Veronique Kitiratschky, Heidelore Hofmann, Peter Kraiczy, Markus M Simon, Reinhard Wallich.   

Abstract

Borrelia burgdorferi complement regulator-acquiring surface protein 1 (CRASP-1), the dominant factor H and FHL-1-binding protein of the Lyme disease spirochete B. burgdorferi, is implicated in pathogen persistence and was recently reported to be nonimmunogenic in humans. Here we show that serum samples from Lyme disease patients contain antibodies with exclusive specificity for nondenatured structural determinants of CRASP-1.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 17000728      PMCID： PMC1698082          DOI： 10.1128/IAI.01028-06

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  29 in total

1.  Evidence that the BBA68 protein (BbCRASP-1) of the Lyme disease spirochetes does not contribute to factor H-mediated immune evasion in humans and other animals.

Authors:  John V McDowell; Kelley M Hovis; Hongming Zhang; Emily Tran; Justin Lankford; R T Marconi
Journal:  Infect Immun       Date:  2006-05       Impact factor: 3.441

2.  Differential binding of host complement inhibitor factor H by Borrelia burgdorferi Erp surface proteins: a possible mechanism underlying the expansive host range of Lyme disease spirochetes.

Authors:  Brian Stevenson; Nazira El-Hage; Melissa A Hines; Jennifer C Miller; Kelly Babb
Journal:  Infect Immun       Date:  2002-02       Impact factor: 3.441

Review 3.  Complement regulator-acquiring surface proteins of Borrelia burgdorferi: a new protein family involved in complement resistance.

Authors:  Peter Kraiczy; Christine Skerka; Peter F Zipfel; Volker Brade
Journal:  Wien Klin Wochenschr       Date:  2002-07-31       Impact factor: 1.704

4.  Human antibody responses to VlsE antigenic variation protein of Borrelia burgdorferi.

Authors:  M B Lawrenz; J M Hardham; R T Owens; J Nowakowski; A C Steere; G P Wormser; S J Norris
Journal:  J Clin Microbiol       Date:  1999-12       Impact factor: 5.948

5.  The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi.

Authors:  J Hellwage; T Meri; T Heikkilä; A Alitalo; J Panelius; P Lahdenne; I J Seppälä; S Meri
Journal:  J Biol Chem       Date:  2000-12-11       Impact factor: 5.157

6.  Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1/reconectin and Factor H.

Authors:  P Kraiczy; C Skerka; M Kirschfink; V Brade; P F Zipfel
Journal:  Eur J Immunol       Date:  2001-06       Impact factor: 5.532

7.  Further characterization of complement regulator-acquiring surface proteins of Borrelia burgdorferi.

Authors:  P Kraiczy; C Skerka; V Brade; P F Zipfel
Journal:  Infect Immun       Date:  2001-12       Impact factor: 3.441

8.  Immune evasion of Borrelia burgdorferi: mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family.

Authors:  Peter Kraiczy; Jens Hellwage; Christine Skerka; Michael Kirschfink; Volker Brade; Peter F Zipfel; Reinhard Wallich
Journal:  Eur J Immunol       Date:  2003-03       Impact factor: 5.532

9.  Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs.

Authors:  Antti Alitalo; Taru Meri; Hilkka Lankinen; Ilkka Seppälä; Pekka Lahdenne; P Scott Hefty; Darrin Akins; Seppo Meri
Journal:  J Immunol       Date:  2002-10-01       Impact factor: 5.422

Review 10.  Factor H family proteins: on complement, microbes and human diseases.

Authors:  P F Zipfel; C Skerka; J Hellwage; S T Jokiranta; S Meri; V Brade; P Kraiczy; M Noris; G Remuzzi
Journal:  Biochem Soc Trans       Date:  2002-11       Impact factor: 5.407
View more
  13 in total

1.  Identification and functional characterisation of Complement Regulator Acquiring Surface Protein-1 of serum resistant Borrelia garinii OspA serotype 4.

Authors:  Nathalie D van Burgel; Peter Kraiczy; Tim J Schuijt; Peter F Zipfel; Alje P van Dam
Journal:  BMC Microbiol       Date:  2010-02-10       Impact factor: 3.605

2.  Borrelia burgdorferi complement regulator-acquiring surface protein 2 (CspZ) as a serological marker of human Lyme disease.

Authors:  Peter Kraiczy; Annekatrin Seling; Catherine A Brissette; Evelyn Rossmann; Klaus-Peter Hunfeld; Tomasz Bykowski; Logan H Burns; Matthew J Troese; Anne E Cooley; Jennifer C Miller; Volker Brade; Reinhard Wallich; Sherwood Casjens; Brian Stevenson
Journal:  Clin Vaccine Immunol       Date:  2007-12-26

Review 3.  Borrelia burgdorferi complement regulator-acquiring surface proteins (BbCRASPs): Expression patterns during the mammal-tick infection cycle.

Authors:  Tomasz Bykowski; Michael E Woodman; Anne E Cooley; Catherine A Brissette; Reinhard Wallich; Volker Brade; Peter Kraiczy; Brian Stevenson
Journal:  Int J Med Microbiol       Date:  2007-12-31       Impact factor: 3.473

Review 4.  Complement regulator-acquiring surface proteins of Borrelia burgdorferi: Structure, function and regulation of gene expression.

Authors:  Peter Kraiczy; Brian Stevenson
Journal:  Ticks Tick Borne Dis       Date:  2012-11-10       Impact factor: 3.744

5.  CspA-mediated binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi.

Authors:  Melisha R Kenedy; Santosh R Vuppala; Corinna Siegel; Peter Kraiczy; Darrin R Akins
Journal:  Infect Immun       Date:  2009-05-18       Impact factor: 3.441

6.  Coordinated expression of Borrelia burgdorferi complement regulator-acquiring surface proteins during the Lyme disease spirochete's mammal-tick infection cycle.

Authors:  Tomasz Bykowski; Michael E Woodman; Anne E Cooley; Catherine A Brissette; Volker Brade; Reinhard Wallich; Peter Kraiczy; Brian Stevenson
Journal:  Infect Immun       Date:  2007-06-11       Impact factor: 3.441

7.  Borrelia burgdorferi surface-localized proteins expressed during persistent murine infection are conserved among diverse Borrelia spp.

Authors:  Jessica L Hughes; Christi L Nolder; Andrew J Nowalk; Dawn R Clifton; Rebekah R Howison; Virginia L Schmit; Robert D Gilmore; James A Carroll
Journal:  Infect Immun       Date:  2008-04-07       Impact factor: 3.441

8.  Borrelia burgdorferi binding of host complement regulator factor H is not required for efficient mammalian infection.

Authors:  Michael E Woodman; Anne E Cooley; Jennifer C Miller; John J Lazarus; Kathryn Tucker; Tomasz Bykowski; Marina Botto; Jens Hellwage; R Mark Wooten; Brian Stevenson
Journal:  Infect Immun       Date:  2007-04-09       Impact factor: 3.441

9.  Delineation of species-specific binding properties of the CspZ protein (BBH06) of Lyme disease spirochetes: evidence for new contributions to the pathogenesis of Borrelia spp.

Authors:  Elizabeth A Rogers; Richard T Marconi
Journal:  Infect Immun       Date:  2007-09-10       Impact factor: 3.441

Review 10.  Lyme Disease Pathogenesis.

Authors:  Jenifer Coburn; Brandon Garcia; Linden T Hu; Mollie W Jewett; Peter Kraiczy; Steven J Norris; Jon Skare
Journal:  Curr Issues Mol Biol       Date:  2020-12-23       Impact factor: 2.081
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.