Literature DB >> 17000349

The prevalence of concern about weight loss and change in eating habits in people with advanced cancer.

Jane B Hopkinson1, David N M Wright, John W McDonald, Jessica L Corner.   

Abstract

Weight loss and anorexia are commonly reported symptoms in people with advanced cancer. Little is known about patient experience of these phenomena, in particular whether they find them of concern. In this study, the prevalence of weight loss and eating-related concern was evaluated in patients with advanced cancer receiving specialist palliative homecare. The survey was a component of a larger study exploring the potential for helping patients and their families live with weight loss and change in eating habits. Patients were under the care of two specialist palliative homecare teams in the south of England in 2003. The questionnaire was distributed to the total eligible caseload of 233 patients with advanced cancer. The response rate was 85%. More than three-quarters of the 199 patients who returned the questionnaires reported weight loss (79%) and/or eating less (76%). Excluding the 32 patients (16%) who had sought help from a family member or friend to complete the questionnaires, more than half (52%) reported concern about weight loss and/or eating. Concern about weight loss or eating was found irrespective of proximity to death. Weight loss and eating-related concerns are commonly experienced by people with advanced cancer receiving palliative homecare. Further work is needed to establish if concerns are amenable to interventions that translate into meaningful outcomes for patients and their families.

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Year:  2006        PMID: 17000349     DOI: 10.1016/j.jpainsymman.2006.05.012

Source DB:  PubMed          Journal:  J Pain Symptom Manage        ISSN: 0885-3924            Impact factor:   3.612


  20 in total

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2.  A cross-sectional study examining the prevalence of cachexia and areas of unmet need in patients with cancer.

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Review 3.  Cancer cachexia, mechanism and treatment.

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4.  Symptoms in advanced pancreatic cancer are of importance for energy intake.

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Journal:  Curr Probl Cancer       Date:  2011 Mar-Apr       Impact factor: 3.187

Review 6.  WITHDRAWN: Interventions for fatigue and weight loss in adults with advanced progressive illness.

Authors:  Cathy Payne; Philip J Wiffen; Suzanne Martin
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7.  The role of thalidomide and placebo for the treatment of cancer-related anorexia-cachexia symptoms: results of a double-blind placebo-controlled randomized study.

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Review 8.  Evolving classification systems for cancer cachexia: ready for clinical practice?

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9.  Alterations in inflammatory biomarkers and energy intake in cancer cachexia: a prospective study in patients with inoperable pancreatic cancer.

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Journal:  Med Oncol       Date:  2016-04-27       Impact factor: 3.064

10.  A TGF-β pathway associated with cancer cachexia.

Authors:  Denis C Guttridge
Journal:  Nat Med       Date:  2015-11       Impact factor: 53.440

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