Literature DB >> 17000251

Impact of the recent randomized trials on the use of progesterone to prevent preterm birth: a 2005 follow-up survey.

Amen Ness1, Todd Dias, Karla Damus, Irina Burd, Vincenzo Berghella.   

Abstract

OBJECTIVE: The purpose of this study was to determine whether current attitudes regarding the use of progesterone to prevent preterm birth have changed since our last survey in 2003. STUDY
DESIGN: We mailed a 20 question survey to 1264 board certified Maternal-Fetal Medicine specialists in the United States between February and March of 2005 asking about their use and attitudes regarding progesterone to prevent preterm birth.
RESULTS: Five hundred and seventy-two surveys were returned (response rate of 45%). In 2005, 67% of respondents used progesterone to prevent SPTB, compared to 38% in 2003 (P < .001). Among users, 38% recommended progesterone for indications other than previous SPTB. Users were more concerned about lack of insurance coverage compared to nonusers but nonusers were more concerned about safety, efficacy, need for more data, and long-term neonatal effects.
CONCLUSION: Although the use of progesterone to prevent PTB has increased significantly since our last survey, there remain a substantial number of nonusers. Among users, many are using it for indications not yet proven in clinical trials. Current nonusers have higher levels of concerns compared to nonusers in the first survey and their major concern is the need for more data.

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Year:  2006        PMID: 17000251     DOI: 10.1016/j.ajog.2006.06.034

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  8 in total

Review 1.  Recurrent preterm birth.

Authors:  Shali Mazaki-Tovi; Roberto Romero; Juan Pedro Kusanovic; Offer Erez; Beth L Pineles; Francesca Gotsch; Pooja Mittal; Nandor Gabor Than; Jimmy Espinoza; Sonia S Hassan
Journal:  Semin Perinatol       Date:  2007-06       Impact factor: 3.300

2.  A national survey examining obstetrician perspectives on use of 17-alpha hydroxyprogesterone caproate post-US FDA approval.

Authors:  Andrei Rebarber; Nathan Fox; Chad K Klauser; Daniel Saltzman; Ashley S Roman
Journal:  Clin Drug Investig       Date:  2013-08       Impact factor: 2.859

3.  Patient characteristics associated with 17-alpha hydroxyprogesterone caproate use among a high-risk cohort.

Authors:  Amy L Turitz; Jamie A Bastek; Stephanie E Purisch; Michal A Elovitz; Lisa D Levine
Journal:  Am J Obstet Gynecol       Date:  2015-10-28       Impact factor: 8.661

Review 4.  Progestin treatment for the prevention of preterm birth.

Authors:  Miha Lucovnik; Ruben J Kuon; Linda R Chambliss; William L Maner; Shao-Qing Shi; Leili Shi; James Balducci; Robert E Garfield
Journal:  Acta Obstet Gynecol Scand       Date:  2011-06-27       Impact factor: 3.636

Review 5.  Progesterone receptors and neural development: a gap between bench and bedside?

Authors:  Christine K Wagner
Journal:  Endocrinology       Date:  2008-02-28       Impact factor: 4.736

6.  Progesterone from maternal circulation binds to progestin receptors in fetal brain.

Authors:  Christine K Wagner; Princy Quadros-Mennella
Journal:  Dev Neurobiol       Date:  2016-10-26       Impact factor: 3.964

7.  STOPPIT Baby Follow-up Study: the effect of prophylactic progesterone in twin pregnancy on childhood outcome.

Authors:  Helen Christine McNamara; Rachael Wood; James Chalmers; Neil Marlow; John Norrie; Graeme MacLennan; Gladys McPherson; Charles Boachie; Jane Elizabeth Norman
Journal:  PLoS One       Date:  2015-04-16       Impact factor: 3.240

8.  Pregnant women's preferences for and concerns about preterm birth prevention: a cross-sectional survey.

Authors:  Vanessa Ha; Sarah D McDonald
Journal:  BMC Pregnancy Childbirth       Date:  2017-01-31       Impact factor: 3.007

  8 in total

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