Literature DB >> 1699978

Cells immunoreactive for neuropeptide in human thymomas.

L Lauriola1, N Maggiano, L M Larocca, F O Ranelletti, R Ricci, M Piantelli, A Capelli.   

Abstract

The presence of opioid peptides, bombesin, and substance P was investigated by immunohistochemistry in tissue sections from six human thymomas. The number of immunoreactive cells seemed to vary from one case to another. Ultrastructural investigation, showing the presence of desmosomes in labelled cells, allowed these cells to be classified as epithelial lineage cells. The occurrence of cells containing neuropeptide in thymomas suggest that peptide molecules could have modulated the behaviour of this tumour, given the reported influence of these molecules on immune functions and their growth promoting activity on several cell types, including mesenchymal and epithelial cells.

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Year:  1990        PMID： 1699978      PMCID： PMC502833          DOI： 10.1136/jcp.43.10.829

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  23 in total

1.  CYTOCHEMICAL DEMONSTRATION OF PEROXIDASE ACTIVITY WITH 3-AMINO-9-ETHYLCARBAZOLE.

Authors:  R C GRAHAM; U LUNDHOLM; M J KARNOVSKY
Journal:  J Histochem Cytochem       Date:  1965-02       Impact factor: 2.479

Review 2.  A role for neuropeptides in the control of cell proliferation.

Authors:  I Zachary; P J Woll; E Rozengurt
Journal:  Dev Biol       Date:  1987-12       Impact factor: 3.582

Review 3.  Regulatory peptides and amines during ontogeny and in non-endocrine cancers: occurrence and possible functional significance.

Authors:  L I Larsson
Journal:  Prog Histochem Cytochem       Date:  1988

4.  The neuroendocrine thymus. Abundant occurrence of oxytocin-, vasopressin-, and neurophysin-like peptides in epithelial cells.

Authors:  U M Moll; B L Lane; F Robert; V Geenen; J J Legros
Journal:  Histochemistry       Date:  1988

5.  Immunoreactive opioid peptides in human breast cancer.

Authors:  L Scopsi; E Balslev; N Brünner; H S Poulsen; J Andersen; F Rank; L I Larsson
Journal:  Am J Pathol       Date:  1989-02       Impact factor: 4.307

6.  Nonspecific immunocytochemical reactions with certain neurohormonal peptides and basic peptide sequences.

Authors:  L Scopsi; B L Wang; L I Larsson
Journal:  J Histochem Cytochem       Date:  1986-11       Impact factor: 2.479

7.  Subpopulations of lymphocytes in human thymomas.

Authors:  L Lauriola; M Piantelli; A Carbone; M A Dina; C Scoppetta; P Musiani
Journal:  Clin Exp Immunol       Date:  1979-09       Impact factor: 4.330

8.  Cortical versus medullary thymomas: a useful morphologic distinction?

Authors:  M J Kornstein; W J Curran; A T Turrisi; J J Brooks
Journal:  Hum Pathol       Date:  1988-11       Impact factor: 3.466

9.  Myasthenic and nonmyasthenic thymoma. An expansion of a minor cortical epithelial cell subset?

Authors:  N Willcox; M Schluep; M A Ritter; H J Schuurman; J Newsom-Davis; B Christensson
Journal:  Am J Pathol       Date:  1987-06       Impact factor: 4.307

10.  Ultrastructural comparison of differentiation of stem cells of murine adenocarcinomas of colon and breast with their normal counterparts.

Authors:  G B Pierce; P K Nakane; A Martinez-Hernandez; J M Ward
Journal:  J Natl Cancer Inst       Date:  1977-05       Impact factor: 13.506
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  3 in total

Review 1.  The thymic education of developing T cells in self neuroendocrine principles.

Authors:  V Geenen; F Robert; H Martens; D De Groote; P Franchimont
Journal:  J Endocrinol Invest       Date:  1992-09       Impact factor: 4.256

2.  Immunohistochemical and in situ hybridization detection of growth-hormone-producing cells in human thymoma.

Authors:  L Lauriola; N Maggiano; F G Serra; S Nori; M L Tardio; A Capelli; M Piantelli; F O Ranelletti
Journal:  Am J Pathol       Date:  1997-07       Impact factor: 4.307

3.  Thymus neuroendocrine tumors with CTNNB1 gene mutations, disarrayed ß-catenin expression, and dual intra-tumor Ki-67 labeling index compartmentalization challenge the concept of secondary high-grade neuroendocrine tumor: a paradigm shift.

Authors:  Alessandra Fabbri; Mara Cossa; Angelica Sonzogni; Paolo Bidoli; Stefania Canova; Diego Cortinovis; Maria Ida Abbate; Fiorella Calabrese; Nazarena Nannini; Francesca Lunardi; Giulio Rossi; Stefano La Rosa; Carlo Capella; Elena Tamborini; Federica Perrone; Adele Busico; Iolanda Capone; Barbara Valeri; Ugo Pastorino; Adriana Albini; Giuseppe Pelosi
Journal:  Virchows Arch       Date:  2017-04-27       Impact factor: 4.064
  3 in total

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