Literature DB >> 16995601

Young stroke, cardiac myxoma, and multiple emboli: a case report and literature review.

Huai-Hua Yeh1, Chi-Chiang Yang, Wai-Fai Tung, Hsin-Fan Wang, Jai-Nien Tung.   

Abstract

Cardiac myxoma is a source of emboli to the vascular tree, especially to the central nervous system. Although it is rare, its early recognition is particularly important because of its unique clinical features of subsequently leading to intracerebral or subarachnoid hemorrhage, even brain metastases, and its potential for surgical cure. Missing the diagnosis may lead to devastating results, including stroke, even sudden death. A 40-year-old male with no other conventional vascular risk factors such as hypertension, diabetes or hyperlipidemia presented with right hemiplegia, global aphasia, vomiting, and fever. Infarction over the left middle cerebral artery was disclosed on magnetic resonance imaging study, and echocardiogram showed a huge mass, about 5cm in size, on the mitral valve which was histopathologically proved to be a cardiac myxoma. He also presented with multiple emboli to the kidneys and the left eye. There is uncertainty about the role of anticoagulation. The treatment of choice remains surgical excision of the cardiac myxoma which may lead to normalization of serum interleukin-6 levels and resolution of constitutional symptoms, and the intracranial aneurysms may regress and resolve.

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Year:  2006        PMID: 16995601

Source DB:  PubMed          Journal:  Acta Neurol Taiwan        ISSN: 1028-768X


  5 in total

1.  Rupture of cerebral myxomatous aneurysm months after resection of the primary cardiac tumor.

Authors:  Christopher S Eddleman; Numa R Gottardi-Littell; Bernard R Bendok; H Hunt Batjer; Richard A Bernstein
Journal:  Neurocrit Care       Date:  2010-10       Impact factor: 3.210

2.  Microemboli monitoring by trans-cranial doppler in patient with acute cardioemboliogenic stroke due to atrial myxoma.

Authors:  Gregory Telman; Orit Mesica; Efim Kouperberg; Oved Cohen; Gil Bolotin; Yoram Agmon
Journal:  Neurol Int       Date:  2010-06-21

Review 3.  Stroke of a cardiac myxoma origin.

Authors:  Shi-Min Yuan; Gulimila Humuruola
Journal:  Rev Bras Cir Cardiovasc       Date:  2015 Mar-Apr

Review 4.  Molecular basis of cardiac myxomas.

Authors:  Pooja Singhal; Adriana Luk; Vivek Rao; Jagdish Butany
Journal:  Int J Mol Sci       Date:  2014-01-20       Impact factor: 5.923

Review 5.  Extracardiac manifestations of atrial myxomas.

Authors:  Braghadheeswar Thyagarajan; Monisha Priyadarshini Kumar; Shil Patel; Abhinav Agrawal
Journal:  J Saudi Heart Assoc       Date:  2016-07-25
  5 in total

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