| Literature DB >> 1699350 |
Abstract
The preS(21-47) sequence of the hepatitis B virus (HBV) envelope protein is involved in binding of the virus to cell receptors. A protein similarity search revealed a partial homology between this sequence and a segment of the human immunoglobulin A (IgA) heavy chain constant region, suggesting that the cell attachment site for HBV might be located on secretory component representing a receptor for polymeric IgA. Data presented herein do not support this hypothesis but provide evidence for immunological cross-reactivity between IgA and the preS(21-47) region of the HBV env protein.Entities:
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Year: 1990 PMID： 1699350 DOI： 10.1016/0042-6822(90)90368-2
Source DB: PubMed Journal: Virology ISSN： 0042-6822 Impact factor: 3.616