Literature DB >> 16989525

Hydroxylated gedunin derivatives from Cedrela sinensis.

Kumiko Mitsui1, Hiroaki Saito, Ryota Yamamura, Haruhiko Fukaya, Yukio Hitotsuyanagi, Koichi Takeya.   

Abstract

Four new limonoids, 11alpha-hydroxygedunin (1), 11beta-hydroxygedunin (2), 7-deacetoxy-7alpha,11alpha-dihydroxygedunin (3), and 7-deacetoxy-7alpha,11beta-dihydroxygedunin (4), were isolated from the cortex of Cedrela sinensis, together with three known compounds, gedunin (5), 7-deacetoxy-7alpha-hydroxygedunin (6), and 11-oxogedunin (7). The structures of 1-4 were determined by a combination of 2D NMR experiments and chemical methods and by X-ray crystallography of 1 and 2.

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Year:  2006        PMID: 16989525     DOI: 10.1021/np068021f

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  3 in total

Review 1.  Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents.

Authors:  Reen-Yen Kuo; Keduo Qian; Susan L Morris-Natschke; Kuo-Hsiung Lee
Journal:  Nat Prod Rep       Date:  2009-08-13       Impact factor: 13.423

2.  6α-Acetoxy-gedunin.

Authors:  Margit Hofer; Harald Greger; Kurt Mereiter
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-07-22

3.  7-Deacetyl-gedunin.

Authors:  Warin Ravangpai; Thapong Theerawattananond; Somjai Pengpreecha; Nongnuj Muangsin; Khanitha Pudhom
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-12-18
  3 in total

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