Literature DB >> 16988319

Case of the month: A case of airway obstruction following tenecteplase administration.

L Kirkham1, J Homewood, P Brook.   

Abstract

The value of thrombolysis in the treatment of acute myocardial infarction is well established. Haemorrhage into subcutaneous tissues is fortunately a rare complication of fibrinolytic administration. However, if as a result of trauma a haematoma develops within the neck following thrombolysis, it can lead to rapid airway compromise. This is the first reported case of tenecteplase administration leading to subcutaneous haemorrhage and consequent airway compromise. It is also the first reported case where the antecedent trauma was a jaw thrust.

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Year:  2006        PMID: 16988319      PMCID: PMC2579612          DOI: 10.1136/emj.2006.038737

Source DB:  PubMed          Journal:  Emerg Med J        ISSN: 1472-0205            Impact factor:   2.740


  6 in total

1.  Uvula hematoma: an unusual complication of streptokinase.

Authors:  P Gill; P Sadler
Journal:  Anesth Analg       Date:  1999-08       Impact factor: 5.108

2.  Prevertebral haematoma after thrombolysis: an unusual cause of airway obstruction.

Authors:  A K Semmonds; S Doherty
Journal:  Emerg Med (Fremantle)       Date:  2001-06

3.  Airway obstruction: a rare complication of thrombolytic therapy.

Authors:  J Ahmed; J Philpott; S Lew-Gor; D Blunt
Journal:  J Laryngol Otol       Date:  2005-10       Impact factor: 1.469

4.  Airway compromise secondary to lingual hematoma complicating administration of tissue plasminogen activator for acute ischemic stroke.

Authors:  H J Shaps; G E Snyder; A E Sama; G S Rudolph
Journal:  Ann Emerg Med       Date:  2001-10       Impact factor: 5.721

5.  Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trial.

Authors:  F Van De Werf; J Adgey; D Ardissino; P W Armstrong; P Aylward; G Barbash; A Betriu; A S Binbrek; R Califf; R Diaz; R Fanebust; K Fox; C Granger; J Heikkilä; S Husted; P Jansky; A Langer; E Lupi; A Maseri; J Meyer; J Mlczoch; D Mocceti; D Myburgh; A Oto; E Paolasso; K Pehrsson; R Seabra-Gomes; L Soares-Piegas; D Sùgrue; M Tendera; E Topol; P Toutouzas; A Vahanian; F Verheugt; L Wallentin; H White
Journal:  Lancet       Date:  1999-08-28       Impact factor: 79.321

6.  Lingual haematoma following treatment with streptokinase and heparin; anaesthetic management.

Authors:  P J Williams; P Jani; J McGlashan
Journal:  Anaesthesia       Date:  1994-05       Impact factor: 6.955

  6 in total

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