Literature DB >> 1698810

Macrophage-colony stimulating factor (M-CSF) in the cerebrospinal fluid.

P Gallo1, S Pagni, B Giometto, M G Piccinno, F Bozza, V Argentiero, B Tavolato.   

Abstract

In a series of 145 cases with neurological diseases, macrophage-colony stimulating factor (M-CSF) was detected in cerebrospinal fluid of patients with brain tumors, bacterial meningitis, and less frequently, AIDS-dementia complex. Granulocyte-colony stimulating factor (G-CSF) was found only in patients with bacterial meningitis; granulocyte-macrophage (GM)-CSF was never detected. These findings suggest that M-CSF may play an important intrathecal immunoregulatory role in neoplastic and infectious diseases of the central nervous system.

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Year:  1990        PMID： 1698810     DOI： 10.1016/0165-5728(90)90152-d

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN： 0165-5728            Impact factor:   3.478


  13 in total

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