| Literature DB >> 16987658 |
José Barluenga1, Fernando Aznar, Ana-Belén García, María-Paz Cabal, Juan J Palacios, María-Angela Menéndez.
Abstract
The synthesis, structure, and biological evaluation of a series of novel rifamycin derivatives, Rifastures (RFA) with potent anti-tuberculosis activity are presented. Some of these derivatives showed higher in vitro activity than rifabutin and rifampicin against not only Mycobacterium tuberculosis strains but also against MAC and Mycobacterium kansasii.Entities:
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Year: 2006 PMID： 16987658 DOI： 10.1016/j.bmcl.2006.08.090
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823