Literature DB >> 16987256

The carcinogenicity of smegma: debunking a myth.

R S Van Howe1, F M Hodges.   

Abstract

BACKGROUND: Smegma is widely believed to cause penile, cervical and prostate cancer. This nearly ubiquitous myth continues to permeate the medical literature despite a lack of valid supportive evidence.
METHODS: A historical perspective of medical ideas pertaining to smegma is provided, and the original studies in both animals and humans are reanalysed using the appropriate statistical methods.
RESULTS: Evidence supporting the role of smegma as a carcinogen is found wanting.
CONCLUSIONS: Assertions that smegma is carcinogenic cannot be justified on scientific grounds.

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Year:  2006        PMID: 16987256     DOI: 10.1111/j.1468-3083.2006.01653.x

Source DB:  PubMed          Journal:  J Eur Acad Dermatol Venereol        ISSN: 0926-9959            Impact factor:   6.166


  10 in total

1.  [Tyson's glands. On eponymic and discussion in urology and dermatology].

Authors:  F H Moll; T Halling; J Leissner; H Fangerau
Journal:  Urologe A       Date:  2015-06       Impact factor: 0.639

Review 2.  Penile cancer: current therapy and future directions.

Authors:  G Sonpavde; L C Pagliaro; C Buonerba; T B Dorff; R J Lee; G Di Lorenzo
Journal:  Ann Oncol       Date:  2013-01-04       Impact factor: 32.976

3.  Inguinal Lymph Nodes in Carcinoma Penis-Observation or Surgery?

Authors:  Syed Althaf; Rajkumar P Narayanakar; Dinesh M Gangaiah; Kapil Dev; Vishnu P Kurpad; Jaiprakash Gurawalia
Journal:  J Clin Diagn Res       Date:  2016-01-01

4.  Penile Nodule: What's Your Diagnosis?

Authors:  Giridhar Guntreddi; Jayasree Vasudevan Nair; Neelima P Theella; Swayam P Nirujogi
Journal:  Cureus       Date:  2021-12-08

5.  Penile mucinous carcinoma: A case report.

Authors:  Hakan Öztürk
Journal:  Oncol Lett       Date:  2014-12-30       Impact factor: 2.967

Review 6.  Updates on the epidemiology and risk factors for penile cancer.

Authors:  Antoin Douglawi; Timothy A Masterson
Journal:  Transl Androl Urol       Date:  2017-10

7.  Clinicopathologic Characteristics and Treatment Outcomes of Penile Cancer.

Authors:  Jong Kil Nam; Dong Hoon Lee; Sung Woo Park; Sung Chul Kam; Ki Soo Lee; Tae Hyo Kim; Taek Sang Kim; Cheol Kyu Oh; Hyun Jun Park; Tae Nam Kim
Journal:  World J Mens Health       Date:  2017-04       Impact factor: 5.400

8.  Microbiology of smegma: Prospective comparative control study.

Authors:  Jae Min Chung; Chang Soo Park; Sang Don Lee
Journal:  Investig Clin Urol       Date:  2019-02-25

9.  Smegma Pearl in a Circumcised Patient: A Case Report.

Authors:  Yaser Mansoor Almutawa; Aneesh Bava; Shana Shirin Najeeb
Journal:  Cureus       Date:  2022-08-28

10.  Critical evaluation of arguments opposing male circumcision: A systematic review.

Authors:  Brian J Morris; Stephen Moreton; John N Krieger
Journal:  J Evid Based Med       Date:  2019-09-08
  10 in total

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