Literature DB >> 169870

A new method for monitoring subclinical virus infections of the central nervous system in mice.

A J Suckling, S Bateman, H E Webb.   

Abstract

The course of a subclinical virus infection of the central nervous system (CNS) of mice has been followed by measuring spontaneous motor activity using Animex equipment. A significant drop in activity occurred on the 5th and 6th day after inoculation with the A774 (avirulent) strain of Semliki Forest virus (SFV) before histological changes were apparent but at the same time as maximum brain virus titre. The relationship of the fall in activity to changes in the pattern of weight gain, food and water intake was also investigated.

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Year:  1975        PMID： 169870      PMCID： PMC2072771     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  7 in total

1.  Changes in drinking and feeding habits of mice with experimental scrapie.

Authors:  G W Outram
Journal:  J Comp Pathol       Date:  1972-10       Impact factor: 1.311

2.  Encephalopathy in mice following inapparent Semliki Forest Virus (S.F.V.) infection.

Authors:  I Zlotnik; D P Grant; D Batter-Hatton
Journal:  Br J Exp Pathol       Date:  1972-04

3.  The virulence of original and derived strains of Semliki forest virus for mice, guinea-pigs and rabbits.

Authors:  C J Bradish; K Allner; H B Maber
Journal:  J Gen Virol       Date:  1971-08       Impact factor: 3.891

4.  Infection patterns in mice of an avirulent and virulent strain of Semliki Forest virus.

Authors:  R Pusztai; E A Gould; H Smith
Journal:  Br J Exp Pathol       Date:  1971-12

5.  An investigation of a new instrument to measure motor activity of small animals.

Authors:  T H Svensson; G Thieme
Journal:  Psychopharmacologia       Date:  1969

6.  Behaviour in emergence and open-field tests of normal and scrapie mice.

Authors:  R J Heitzman; C R Corp
Journal:  Res Vet Sci       Date:  1968-11       Impact factor: 2.534

7.  The course of Semliki Forest virus infection in mice.

Authors:  J Seamer; W J Randles; R Fitzgeorge
Journal:  Br J Exp Pathol       Date:  1967-08
  7 in total
  2 in total

1.  Motor activity changes in scrapie-affected mice.

Authors:  A J Suckling; S Bateman; C B Waldron; H E Webb; R H Kimberlin
Journal:  Br J Exp Pathol       Date:  1976-12

2.  The relationship between axonal transport of protein and demyelination in the optic nerves of mice infected with Semliki Forest virus.

Authors:  E M Tansey; H Ikeda
Journal:  Brain Res       Date:  1986-11-05       Impact factor: 3.252
  2 in total

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