| Literature DB >> 16986923 |
Gang Xu1, Ai-Jun Hou, Rui-Rui Wang, Guang-Yu Liang, Yong-Tang Zheng, Ze-Yuan Liu, Xiao-Li Li, Yu Zhao, Sheng-Xiong Huang, Li-Yan Peng, Qin-Shi Zhao.
Abstract
Przewalskin A (1), a novel C23 terpenoid with a 6/6/7 carbon ring skeleton, was isolated from Salvia przewalskii. Its structure was determined by comprehensive 1D NMR, 2D NMR, and MS spectroscopic analysis and subsequently confirmed by a single-crystal X-ray diffraction study of its PDC oxidation derivative (2). Compounds 1 and 2 showed modest anti-HIV-1 activity with EC50 = 41 and 89 microg/mL, respectively.Entities:
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Year: 2006 PMID： 16986923 DOI： 10.1021/ol061609t
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005