Literature DB >> 16986922

The 1H NMR method for the determination of the absolute configuration of 1,2,3-prim,sec,sec-triols.

Enrique Lallana1, Félix Freire, José Manuel Seco, Emilio Quiñoa, Ricardo Riguera.   

Abstract

The absolute configuration of 1,2,3-prim,sec,sec-triols can be assigned by comparison of the 1H NMR spectra of the tris-(R)- and the tris-(S)-MPA ester derivatives. An experimental demonstration of this correlation with 24 triols of known absolute configuration and a protocol using two parameters-Deltadelta(RS)(H3) and the difference between Deltadelta RS (H2) and Deltadelta RS (H3) = absolute value (Delta(Deltadelta RS))-for its application to the determination of the absolute configuration of other triols are presented.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16986922     DOI： 10.1021/ol0616135

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  An ingenious method for the determination of the relative and absolute configurations of compounds containing aryl-glycerol fragments by 1H NMR spectroscopy.

Authors:  Xu Zhang; Kai-Zhou Lu; Hai-Wei Yan; Zi-Ming Feng; Ya-Nan Yang; Jian-Shuang Jiang; Pei-Cheng Zhang
Journal:  RSC Adv       Date:  2021-02-19       Impact factor: 3.361

2.  Determination of the absolute stereostructure of a cyclic azobenzene from the crystal structure of the precursor containing a heavy element.

Authors:  Reji Thomas; Nobuyuki Tamaoki
Journal:  Beilstein J Org Chem       Date:  2016-10-19       Impact factor: 2.883
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.