Literature DB >> 169867

Loss of anti-tumour immunogenicity of a somatic cell hybrid line with increasing subculture.

R Favre, Y Carcassonne, G Meyer.   

Abstract

Good immunoprotection was afforded by A9/SEWA somatic hybrid cells in the C3H mouse/C3H Py tumour system, confirming results previously obtained in the A.SW mouse/SEWA tumour system. However, in this study the immunogenicity decreased with increasing serial subculture of the hybrid line and concomitant chromosome loss.

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Mesh：

Year:  1975        PMID： 169867      PMCID： PMC2024787          DOI： 10.1038/bjc.1975.140

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  6 in total

1.  Viral carcinogenesis.

Authors:  R DULBECCO
Journal:  Cancer Res       Date:  1961-09       Impact factor: 12.701

2.  [Protection afforded by hybrid cells against the inoculation of the parental tumour line (author's transl)].

Authors:  R Favre; J Filipczyk; M Berebbi; G Meyer
Journal:  Ann Immunol (Paris)       Date:  1974 Mar-Apr

3.  Expression of polyoma-induced antigens in low malignant hybrids derived from fusion of a polyoma-induced tumour with a fibroblast line.

Authors:  G Meyer; M Berebbi; G Klein
Journal:  Nature       Date:  1974-05-03       Impact factor: 49.962

4.  [Comparative study of the protective capacity of virus and allogenic, transformed cells in the polyoma virus-mouse system].

Authors:  R Favre; G Meyer
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1972-10-16

5.  Tumor hybrid cells: an immunotherapeutic agent.

Authors:  R Parkman
Journal:  J Natl Cancer Inst       Date:  1974-05       Impact factor: 13.506

6.  Suppression of malignancy by cell fusion.

Authors:  H Harris; O J Miller; G Klein; P Worst; T Tachibana
Journal:  Nature       Date:  1969-07-26       Impact factor: 49.962
  6 in total

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