Literature DB >> 16985634

Pharmacotherapy for stress urinary incontinence.

Tracy W Cannon, Michael B Chancellor.   

Abstract

The purpose of this review article is to highlight new pharmacotherapies on the horizon for the treatment of stress urinary incontinence. Although behavioral and surgical therapies are currently the mainstay of treatment for this condition, we are hopeful that pharmacotherapy will one day take center stage of the various treatment options. Currently, there are no medications approved by the US Food and Drug Administration for the treatment of stress urinary incontinence. However, exciting clinical data are becoming available about an oral medication for the treatment of stress urinary incontinence that appears to be clinically safe and efficacious. In addition to discussing medications currently under development, this article also discusses pharmacologic targets that could be suitable future targets to treat stress urinary incontinence.

Entities:  

Year:  2003        PMID： 16985634      PMCID： PMC1473013     

Source DB:  PubMed          Journal:  Rev Urol        ISSN： 1523-6161


  35 in total

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Journal:  Br J Pharmacol       Date:  1996-05       Impact factor: 8.739

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Journal:  Obstet Gynecol       Date:  1996-12       Impact factor: 7.661

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Journal:  Br J Obstet Gynaecol       Date:  1990-09

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Journal:  Obstet Gynecol       Date:  1998-03       Impact factor: 7.661

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Authors:  L Wilson; J S Brown; G P Shin; K O Luc; L L Subak
Journal:  Obstet Gynecol       Date:  2001-09       Impact factor: 7.661

6.  Unmasking of a neonatal somatovesical reflex in adult cats by the serotonin autoreceptor agonist 5-methoxy-N,N-dimethyltryptamine.

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Journal:  Brain Res Dev Brain Res       Date:  1990-06-01

7.  Comparison of the effects of serotonin selective, norepinephrine selective, and dual serotonin and norepinephrine reuptake inhibitors on lower urinary tract function in cats.

Authors:  Mary A Katofiasc; Jeffrey Nissen; James E Audia; Karl B Thor
Journal:  Life Sci       Date:  2002-08-02       Impact factor: 5.037

8.  Experimental evidence for a central nervous system site of action in the effect of alpha-adrenergic blockers on the external urinary sphincter.

Authors:  J Gajewski; J W Downie; S A Awad
Journal:  J Urol       Date:  1984-08       Impact factor: 7.450

9.  The effects of birth on urinary continence mechanisms and other pelvic-floor characteristics.

Authors:  S Meyer; A Schreyer; P De Grandi; P Hohlfeld
Journal:  Obstet Gynecol       Date:  1998-10       Impact factor: 7.661

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Authors:  H Danuser; K B Thor
Journal:  J Urol       Date:  1995-04       Impact factor: 7.450
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  2 in total

1.  Neurophysiology of lower urinary tract function and dysfunction.

Authors:  Naoki Yoshimura; Michael B Chancellor
Journal:  Rev Urol       Date:  2003

Review 2.  The treatment of female stress urinary incontinence: an evidenced-based review.

Authors:  Anne P Cameron; Allen McNeil Haraway
Journal:  Open Access J Urol       Date:  2011-06-17
  2 in total

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