Literature DB >> 16984116

Experimental model of hemorrhagic stroke: rabbit immunization with HL-60 promyelocytic cell differentiation factor.

M V Gapon1, S M Dranitsyna, N I Minkevich, M A Gruden', I I Babichenko, I A Kostanyan.   

Abstract

Rabbits immunized with synthetic HLDF differentiation factor developed hemorrhagic stroke with thrombosis of small cerebral vessels and destruction of vascular endotheliocytes. The severity of stroke correlated with serum level of antibodies to differentiation factor. The role of different sites of HLDF molecule in the induction of clinical signs of hemorrhagic stroke was studied.

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Year:  2006        PMID: 16984116     DOI: 10.1007/s10517-006-0147-7

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  1 in total

Review 1.  The use of animal models for stroke research: a review.

Authors:  Juliana B Casals; Naira C G Pieri; Matheus L T Feitosa; Anna C M Ercolin; Kelly C S Roballo; Rodrigo S N Barreto; Fabiana F Bressan; Daniele S Martins; Maria A Miglino; Carlos E Ambrósio
Journal:  Comp Med       Date:  2011-08       Impact factor: 0.982

  1 in total

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