Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 JmjC-domain-containing proteins and histone demethylation.

Literature DB >> 16983801

JmjC-domain-containing proteins and histone demethylation.

Robert J Klose¹, Eric M Kallin, Yi Zhang.

Abstract

Histone methylation has important roles in regulating gene expression and forms part of the epigenetic memory system that regulates cell fate and identity. Enzymes that directly remove methyl marks from histones have recently been identified, revealing a new level of plasticity within this epigenetic modification system. Here we analyse the evolutionary relationship between Jumonji C (JmjC)-domain-containing proteins and discuss their cellular functions in relation to their potential enzymatic activities.

Mesh：

Substances：

Year: 2006 PMID： 16983801 DOI： 10.1038/nrg1945

Source DB: PubMed Journal: Nat Rev Genet ISSN： 1471-0056 Impact factor: 53.242

Keyword Cloud
Cited

529 in total

1. KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation.

Authors: Datsun A Hsia; Clifford G Tepper; Mamata R Pochampalli; Elaine Y C Hsia; Chie Izumiya; Steve B Huerta; Michael E Wright; Hong-Wu Chen; Hsing-Jien Kung; Yoshihiro Izumiya
Journal: Proc Natl Acad Sci U S A Date: 2010-05-10 Impact factor: 11.205

2. Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.

Authors: Tsuyoshi Osawa; Masashi Muramatsu; Feng Wang; Rika Tsuchida; Tatsuhiko Kodama; Takashi Minami; Masabumi Shibuya
Journal: Proc Natl Acad Sci U S A Date: 2011-12-05 Impact factor: 11.205

3. The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation.

Authors: Fu Huang; Mahesh B Chandrasekharan; Yi-Chun Chen; Srividya Bhaskara; Scott W Hiebert; Zu-Wen Sun
Journal: J Biol Chem Date: 2010-06-09 Impact factor: 5.157

4. Miz1 Controls Schwann Cell Proliferation via H3K36^me2 Demethylase Kdm8 to Prevent Peripheral Nerve Demyelination.

Authors: David Fuhrmann; Marco Mernberger; Andrea Nist; Thorsten Stiewe; Hans-Peter Elsässer
Journal: J Neurosci Date: 2017-12-07 Impact factor: 6.167

Review 5. Somatic Cell Nuclear Transfer Reprogramming: Mechanisms and Applications.

Authors: Shogo Matoba; Yi Zhang
Journal: Cell Stem Cell Date: 2018-07-19 Impact factor: 24.633

Review 6. X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

Authors: Rossella Tricarico; Emmanuelle Nicolas; Michael J Hall; Erica A Golemis
Journal: Clin Cancer Res Date: 2020-07-30 Impact factor: 12.531

Review 7. Epigenetics and the environment: in search of the "toleroasome" vital to execution of ischemic preconditioning.

Authors: David Brand; Rajiv R Ratan
Journal: Transl Stroke Res Date: 2013-01-08 Impact factor: 6.829

JmjC-domain-containing proteins and histone demethylation.

1. KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation.

2. Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.

3. The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation.

4. Miz1 Controls Schwann Cell Proliferation via H3K36^me2 Demethylase Kdm8 to Prevent Peripheral Nerve Demyelination.

Review 5. Somatic Cell Nuclear Transfer Reprogramming: Mechanisms and Applications.

Review 6. X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

Review 7. Epigenetics and the environment: in search of the "toleroasome" vital to execution of ischemic preconditioning.

Review 8. An epigenetic perspective on the free radical theory of development.

9. The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer.

Review 10. New Insights into Protein Hydroxylation and Its Important Role in Human Diseases.

JmjC-domain-containing proteins and histone demethylation.

1. KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation.

2. Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.

3. The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation.

4. Miz1 Controls Schwann Cell Proliferation via H3K36me2 Demethylase Kdm8 to Prevent Peripheral Nerve Demyelination.

Review 5. Somatic Cell Nuclear Transfer Reprogramming: Mechanisms and Applications.

Review 6. X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

Review 7. Epigenetics and the environment: in search of the "toleroasome" vital to execution of ischemic preconditioning.

Review 8. An epigenetic perspective on the free radical theory of development.

9. The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer.

Review 10. New Insights into Protein Hydroxylation and Its Important Role in Human Diseases.

4. Miz1 Controls Schwann Cell Proliferation via H3K36^me2 Demethylase Kdm8 to Prevent Peripheral Nerve Demyelination.