Literature DB >> 16983130

Medication dispensing errors and potential adverse drug events before and after implementing bar code technology in the pharmacy.

Eric G Poon1, Jennifer L Cina, William Churchill, Nirali Patel, Erica Featherstone, Jeffrey M Rothschild, Carol A Keohane, Anthony D Whittemore, David W Bates, Tejal K Gandhi.   

Abstract

BACKGROUND: Many dispensing errors made in hospital pharmacies can harm patients. Some hospitals are investing in bar code technology to reduce these errors, but data about its efficacy are limited.
OBJECTIVE: To evaluate whether implementation of bar code technology reduced dispensing errors and potential adverse drug events (ADEs).
DESIGN: Before-and-after study using direct observations.
SETTING: Hospital pharmacy at a 735-bed tertiary care academic medical center. INTERVENTION: A bar code-assisted dispensing system was implemented in 3 configurations. In 2 configurations, all doses were scanned once during the dispensing process. In the third configuration, only 1 dose was scanned if several doses of the same medication were being dispensed. MEASUREMENTS: Target dispensing errors, defined as dispensing errors that bar code technology was designed to address, and target potential ADEs, defined as target dispensing errors that can harm patients.
RESULTS: In the pre- and post-bar code implementation periods, the authors observed 115,164 and 253,984 dispensed medication doses, respectively. Overall, the rates of target potential ADEs and all potential ADEs decreased by 74% and 63%, respectively. Of the 3 configurations of bar code technology studied, the 2 configurations that required staff to scan all doses had a 93% to 96% relative reduction in the incidence of target dispensing errors (P < 0.001) and 86% to 97% relative reduction in the incidence of potential ADEs (P < 0.001). However, the configuration that did not require scanning of every dose had only a 60% relative reduction in the incidence of target dispensing errors (P < 0.001) and an increased (by 2.4-fold) incidence of target potential ADEs (P = 0.014). There were several potentially life-threatening ADEs involving intravenous dopamine and intravenous heparin in that configuration. LIMITATIONS: The authors used surrogate outcomes; did not mask assessors to the purpose of study; and excluded the controlled substance fill process (a process with low error rates at baseline) from the study, which may bias the combined decrease in error rates toward a larger magnitude.
CONCLUSIONS: The overall rates of dispensing errors and potential ADEs substantially decreased after implementing bar code technology. However, the technology should be configured to scan every dose during the dispensing process.

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Year:  2006        PMID: 16983130     DOI: 10.7326/0003-4819-145-6-200609190-00006

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN: 0003-4819            Impact factor:   25.391


  54 in total

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9.  Medication dispensing errors in a French military hospital pharmacy.

Authors:  Xavier Bohand; Olivier Aupée; Patrick Le Garlantezec; Hélène Mullot; Leslie Lefeuvre; Laurent Simon
Journal:  Pharm World Sci       Date:  2009-03-21

10.  Intervention to reduce the use of unsafe abbreviations in a teaching hospital.

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