Literature DB >> 16983033

Laparoscopic-assisted pancreatic necrosectomy: A new surgical option for treatment of severe necrotizing pancreatitis.

Dilip Parekh1.   

Abstract

HYPOTHESIS: Open surgery for pancreatic debridement is often associated with major morbidity such as wound complications, fascial dehiscence, and intestinal fistulae. Hand-assisted laparoscopic surgery (HALS) is useful for complex abdominal procedures since the benefits of traditional laparoscopic surgery are retained. Published experience with HALS for pancreatic debridement is limited to anecdotal case reports.
SETTING: University-affiliated private and public hospitals. PATIENTS: Twenty-three patients with necrotizing pancreatitis were evaluated and 19 patients underwent pancreatic debridement from 2001 to 2006. A GelPort (Applied Medical, Rancho Santa Margarita, Calif) was used to provide laparoscopic hand access. In the majority of the patients, an infracolic approach was used to access the pancreatic necrosis.
RESULTS: Nineteen patients underwent laparoscopic evacuation of pancreatic necrosis, and in 18 patients, the procedure was completed. The mean age was 54 years; the mean +/- SEM body mass index, calculated as weight in kilograms divided by height in meters squared, was 32.0 +/- 2.6; the mean American Society of Anesthesiologists score was 3.4; and 7 of 19 patients had past history organ failure. The mean +/- SEM operating time was 153 +/- 10 minutes and mean +/- SEM blood loss was 352.6 +/- 103 mL. Four patients required reoperations, 2 using HALS and 2 open. There were no postoperative complications related to the HAL procedure itself, such as major wound infections, intestinal fistulae, or postoperative hemorrhage. Postoperative computed tomographic scans confirmed adequacy of debridement. The mean +/- SEM length of hospital stay after surgery was 16.3 +/- 3.8 days.
CONCLUSIONS: This is the largest reported study of laparoscopic debridement for pancreatic necrosis. The procedure is feasible and associated with a low morbidity and mortality. Pancreatic debridement with HALS may provide a new option for the surgical treatment of selected patients with severe necrotizing pancreatitis.

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Year:  2006        PMID: 16983033     DOI: 10.1001/archsurg.141.9.895

Source DB:  PubMed          Journal:  Arch Surg        ISSN: 0004-0010


  38 in total

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2.  The role of laparoendoscopic surgery in acute pancreatitis.

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Authors:  George Rossidis; Steven J Hughes
Journal:  Curr Gastroenterol Rep       Date:  2012-04

4.  Management of infected pancreatic necrosis using retroperitoneal necrosectomy with flexible endoscope: 10 years of experience.

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5.  Getting the dead out: modern treatment strategies for necrotizing pancreatitis.

Authors:  Monica M Dua; David J Worhunsky; Sabina Amin; John D Louie; Walter G Park; George Triadafilopoulos; Brendan C Visser
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6.  Transluminal retroperitoneal endoscopic necrosectomy with the use of hydrogen peroxide and without external irrigation: a novel approach for the treatment of walled-off pancreatic necrosis.

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7.  Recurrent pancreatitis caused by ampullary carcinoma and minor papilla adenoma in familial polyposis: report of a case.

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Review 8.  Minimally invasive management of pancreatic abscess, pseudocyst, and necrosis: a systematic review of current guidelines.

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9.  Characteristics and outcomes of patients undergoing debridement of pancreatic necrosis.

Authors:  Sebron Harrison; Manasi Kakade; Shyam Varadarajula; Justin Parden; Desiree Morgan; John Christein
Journal:  J Gastrointest Surg       Date:  2009-11-25       Impact factor: 3.452

10.  Early complications after interventions in patients with acute pancreatitis.

Authors:  Ai-Lin Wei; Qiang Guo; Ming-Jun Wang; Wei-Ming Hu; Zhao-Da Zhang
Journal:  World J Gastroenterol       Date:  2016-03-07       Impact factor: 5.742

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