Literature DB >> 16982571

A common cognitive profile in elderly fallers and in patients with Parkinson's disease: the prominence of impaired executive function and attention.

Jeffrey M Hausdorff1, Glen M Doniger, Shmuel Springer, Galit Yogev, Ely S Simon, Nir Giladi.   

Abstract

The present study examined the cognitive profile of elderly fallers relative to healthy elderly controls and patients with Parkinson's disease (PD), a positive-control group, using a computerized battery. Fallers performed more poorly than controls on executive function, attention, and motor skills, but performed comparably on memory, information processing and the Mini-Mental State Examination. A similar profile was evident for PD patients. However, unlike PD patients, fallers were abnormally inconsistent in their reaction times. These findings indicate that elderly fallers may have a unique cognitive processing deficit (i.e., variability of response timing) and underscore the importance of executive function and attention as potential targets for fall risk screening and interventions.

Entities:  

Mesh:

Year:  2006        PMID: 16982571      PMCID: PMC1868891          DOI: 10.1080/03610730600875817

Source DB:  PubMed          Journal:  Exp Aging Res        ISSN: 0361-073X            Impact factor:   1.645


  30 in total

1.  Dissociation of attentional processes in patients with focal frontal and posterior lesions.

Authors:  D T Stuss; J P Toth; D Franchi; M P Alexander; S Tipper; F I Craik
Journal:  Neuropsychologia       Date:  1999-08       Impact factor: 3.139

2.  Executive function in Parkinson's disease and subcortical disorders.

Authors:  J W Elias; J E Treland
Journal:  Semin Clin Neuropsychiatry       Date:  1999-01

3.  Choice stepping reaction time: a composite measure of falls risk in older people.

Authors:  S R Lord; R C Fitzpatrick
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2001-10       Impact factor: 6.053

4.  Different cognitive functions in relation to falls among older persons. Immediate memory as an independent risk factor for falls.

Authors:  Natasja M van Schoor; Johannes H Smit; Saskia M F Pluijm; Cees Jonker; Paul Lips
Journal:  J Clin Epidemiol       Date:  2002-09       Impact factor: 6.437

5.  Differential executive control impairments in early Parkinson's disease.

Authors:  J Uekermann; I Daum; M Bielawski; S Muhlack; S Peters; H Przuntek; T Mueller
Journal:  J Neural Transm Suppl       Date:  2004

6.  Parkinsonism: onset, progression and mortality.

Authors:  M M Hoehn; M D Yahr
Journal:  Neurology       Date:  1967-05       Impact factor: 9.910

7.  Effects of cognitive challenge on gait variability in patients with Parkinson's disease.

Authors:  Jeffrey M Hausdorff; Jackov Balash; Nir Giladi
Journal:  J Geriatr Psychiatry Neurol       Date:  2003-03       Impact factor: 2.680

8.  Staying on the job: the frontal lobes control individual performance variability.

Authors:  Donald T Stuss; Kelly J Murphy; Malcolm A Binns; Michael P Alexander
Journal:  Brain       Date:  2003-07-22       Impact factor: 13.501

9.  Progression of gait disorder and rigidity and risk of death in older persons.

Authors:  R S Wilson; J A Schneider; L A Beckett; D A Evans; D A Bennett
Journal:  Neurology       Date:  2002-06-25       Impact factor: 9.910

10.  Validity of a novel computerized cognitive battery for mild cognitive impairment.

Authors:  Tzvi Dwolatzky; Victor Whitehead; Glen M Doniger; Ely S Simon; Avraham Schweiger; Dena Jaffe; Howard Chertkow
Journal:  BMC Geriatr       Date:  2003-11-02       Impact factor: 3.921

View more
  63 in total

1.  Postural instability and fall risk in Parkinson's disease: impaired dual tasking, pacing, and bilateral coordination of gait during the "ON" medication state.

Authors:  Meir Plotnik; Nir Giladi; Yaacov Dagan; Jeffery M Hausdorff
Journal:  Exp Brain Res       Date:  2011-01-30       Impact factor: 1.972

2.  Why does older adults' balance become less stable when walking and performing a secondary task? Examination of attentional switching abilities.

Authors:  Teresa D Hawkes; Ka-Chun Siu; Patima Silsupadol; Marjorie H Woollacott
Journal:  Gait Posture       Date:  2011-10-02       Impact factor: 2.840

Review 3.  Examining the relationship between specific cognitive processes and falls risk in older adults: a systematic review.

Authors:  C L Hsu; L S Nagamatsu; J C Davis; T Liu-Ambrose
Journal:  Osteoporos Int       Date:  2012-05-26       Impact factor: 4.507

4.  Utility of the NeuroTrax computerized battery for cognitive screening in Parkinson's disease: comparison with the MMSE and the MoCA.

Authors:  B Hanna-Pladdy; A Enslein; M Fray; B J Gajewski; R Pahwa; K E Lyons
Journal:  Int J Neurosci       Date:  2010-08       Impact factor: 2.292

Review 5.  Assessing the interplay between cognition and gait in the clinical setting.

Authors:  A H Snijders; C C Verstappen; M Munneke; B R Bloem
Journal:  J Neural Transm (Vienna)       Date:  2007-07-06       Impact factor: 3.575

Review 6.  Gait dynamics, fractals and falls: finding meaning in the stride-to-stride fluctuations of human walking.

Authors:  Jeffrey M Hausdorff
Journal:  Hum Mov Sci       Date:  2007-07-05       Impact factor: 2.161

7.  Cognitive and motor function are associated following mild traumatic brain injury.

Authors:  Jacob J Sosnoff; Steven P Broglio; Michael S Ferrara
Journal:  Exp Brain Res       Date:  2008-02-27       Impact factor: 1.972

8.  Intraindividual variability in executive functions but not speed of processing or conflict resolution predicts performance differences in gait speed in older adults.

Authors:  Roee Holtzer; Jeannette Mahoney; Joe Verghese
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2013-11-27       Impact factor: 6.053

Review 9.  Where attention falls: Increased risk of falls from the converging impact of cortical cholinergic and midbrain dopamine loss on striatal function.

Authors:  Martin Sarter; Roger L Albin; Aaron Kucinski; Cindy Lustig
Journal:  Exp Neurol       Date:  2014-05-05       Impact factor: 5.330

10.  Neurocognitive evaluation of brain metastases patients treated with post-resection stereotactic radiosurgery: a prospective single arm clinical trial.

Authors:  Assaf Berger; Ido Strauss; Shlomit Ben Moshe; Benjamin W Corn; Dror Limon; Nathan Shtraus; Tal Shahar; Andrew A Kanner
Journal:  J Neurooncol       Date:  2018-08-04       Impact factor: 4.130

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.