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Literature DB >> 16980465

Transcription modulation of Salmonella enterica serovar Typhimurium promoters by sub-MIC levels of rifampin.

Grace Yim¹, Fernando de la Cruz, George B Spiegelman, Julian Davies.

Abstract

Promoter-lux fusions that showed rifampin-modulated transcription were identified from a Salmonella enterica serovar Typhimurium 14028 reporter library. The transformation of a subset of fusions into mutants that lacked one of six global regulatory proteins or were rifampin resistant showed that transcription modulation was independent of the global regulators, promoter specific, and dependent on the interaction of rifampin with RNA polymerase.

Entities: Chemical Species

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Year: 2006 PMID： 16980465 PMCID： PMC1636311 DOI： 10.1128/JB.00791-06

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

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