| Literature DB >> 16979636 |
Wendy J Watkins1, Alexandra J Umbers, Kathryn J Woad, Sarah E Harris, Ingrid M Winship, Ksenija Gersak, Andrew N Shelling.
Abstract
FOXO3A and FOXO1A are excellent candidate genes for the development of premature ovarian failure and have not been analyzed previously in POF patients. Potentially causal mutations in FOXO3A (2/90; 2.2%) and FOXO1A (1/90; 1.1%) were identified in POF patients; however, the pathological role of these mutations will be determined only by screening increased numbers of patients and controls, or by functional studies.Entities:
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Year: 2006 PMID： 16979636 DOI： 10.1016/j.fertnstert.2006.03.054
Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329