Literature DB >> 16979574

Transforming growth factor-beta: taking control of T cells' life and death.

David A Horwitz1.   

Abstract

To determine how transforming growth factor-beta (TGF-beta) controls T cell function, Marie et al. (2006) and Li et al. (2006a) created mice with T cells lacking TGF-beta signaling receptors. Both report that TGF-beta signaling by T cells is absolutely essential for tolerance and homeostasis.

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Year:  2006        PMID： 16979574     DOI： 10.1016/j.immuni.2006.08.013

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  4 in total

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  4 in total

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