Literature DB >> 16978911

Current surgical treatment of squamous cell carcinoma of the head and neck.

Mike Yao1, Joel B Epstein, Bijal J Modi, Kristen B Pytynia, Arno J Mundt, Lawrence E Feldman.   

Abstract

Historically treatment of head and neck cancers involved surgical resection followed by radiation therapy for advanced tumors. Concurrent chemoradiation therapies have shown equal survival to surgical resection with better preservation of function. However, concurrent therapy does entail significant morbidity, and recent advances have been used to minimize that morbidity. Newer tumor specific medical therapies are anticipated to be less toxic while maintaining a high degree of efficacy. For resectable cancer, transoral laser microsurgery is a new trend in surgery for complete resection of tumors with preservation of function. Advanced reconstructive techniques that allow free transfer of soft tissue and bone from all over the body improve the functional and aesthetic outcomes following major ablative surgery. With successful surgical reconstruction, dental and prosthetic rehabilitation choices are enhanced. Advances in rehabilitation of speech following removal of the larynx have improved the quality of life post-laryngectomy patients. With these newer therapies and methods of reconstruction, each patient needs to be carefully evaluated to maximize the possibility of cure and level of function, and minimize the morbidity associated with treatment. Combined chemotherapy and radiation protocols are associated with increased acute and chronic toxicities that may affect the quality of life due to the impact upon oral disease and oral function. Oral care providers must be aware of advances in cancer management and implications for patient care to effectively care for these patients.

Entities:  

Mesh:

Year:  2006        PMID: 16978911     DOI: 10.1016/j.oraloncology.2006.04.013

Source DB:  PubMed          Journal:  Oral Oncol        ISSN: 1368-8375            Impact factor:   5.337


  15 in total

1.  Topical application of platelet supernatant gel in the management of radiotherapy-induced mucositis: a case report.

Authors:  Mario Di Staso; Anna Rughetti; Luigi Dell'Orso; Francesco Marampon; Maria Emilia La Verghetta; Silvia Parente; Giovanni Luca Gravina; Federica Aielli; Vincenza Dolo; Valeria Ruggieri; Pietro Franzese; Pierluigi Bonfili; Vincenzo Tombolini; Ernesto Di Cesare
Journal:  Blood Transfus       Date:  2013-10-22       Impact factor: 3.443

2.  Detection of TIMP3 promoter hypermethylation in salivary rinse as an independent predictor of local recurrence-free survival in head and neck cancer.

Authors:  Wenyue Sun; David Zaboli; Hao Wang; Yan Liu; Demetri Arnaoutakis; Tanbir Khan; Zubair Khan; Wayne M Koch; Joseph A Califano
Journal:  Clin Cancer Res       Date:  2012-01-06       Impact factor: 12.531

Review 3.  Essentials of oral cancer.

Authors:  César Rivera
Journal:  Int J Clin Exp Pathol       Date:  2015-09-01

4.  Autocrine IL-1β-TRAF6 signalling promotes squamous cell carcinoma invasion through paracrine TNFα signalling to carcinoma-associated fibroblasts.

Authors:  S I Chaudhry; S Hooper; E Nye; P Williamson; K Harrington; E Sahai
Journal:  Oncogene       Date:  2012-03-26       Impact factor: 9.867

5.  ECRG4 inhibits growth and invasiveness of squamous cell carcinoma of the head and neck in vitro and in vivo.

Authors:  Ting Xu; Dajiang Xiao; Xin Zhang
Journal:  Oncol Lett       Date:  2013-04-10       Impact factor: 2.967

6.  Heat generation and transfer behaviors of ti-coated carbon steel rod adaptable for ablation therapy of oral cancer.

Authors:  Takashi Naohara; Hiromichi Aono; Tsunehiro Maehara; Hideyuki Hirazawa; Shinya Matsutomo; Yuji Watanabe
Journal:  J Funct Biomater       Date:  2013-02-18

7.  Head and Neck Cancer Detection in Digitized Whole-Slide Histology Using Convolutional Neural Networks.

Authors:  Martin Halicek; Maysam Shahedi; James V Little; Amy Y Chen; Larry L Myers; Baran D Sumer; Baowei Fei
Journal:  Sci Rep       Date:  2019-10-01       Impact factor: 4.379

8.  Elective neck dissection versus "wait and watch" policy in tongue carcinoma.

Authors:  Satish Kumaran Pugazhendi; Lalitha Thambiah; Anuradha Venkatasetty; Vinod Thangaswamy
Journal:  J Pharm Bioallied Sci       Date:  2012-08

9.  Expression of cytosolic malic enzyme (ME1) is associated with disease progression in human oral squamous cell carcinoma.

Authors:  Chie Nakashima; Kazuhiko Yamamoto; Rina Fujiwara-Tani; Yi Luo; Sayako Matsushima; Kiyomu Fujii; Hitoshi Ohmori; Tomonori Sasahira; Takamitsu Sasaki; Yasuhiko Kitadai; Tadaaki Kirita; Hiroki Kuniyasu
Journal:  Cancer Sci       Date:  2018-05-01       Impact factor: 6.716

10.  Hyperspectral Imaging of Head and Neck Squamous Cell Carcinoma for Cancer Margin Detection in Surgical Specimens from 102 Patients Using Deep Learning.

Authors:  Martin Halicek; James D Dormer; James V Little; Amy Y Chen; Larry Myers; Baran D Sumer; Baowei Fei
Journal:  Cancers (Basel)       Date:  2019-09-14       Impact factor: 6.639

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