Literature DB >> 16978536

DC-SIGN and immunoregulation.

Tong Zhou1, Yongxi Chen, Li Hao, Yanyun Zhang.   

Abstract

Dendritic cells (DCs) are known to be the most powerful professional antigen-presenting cells so far. It could activate primary immune response, and also downregulate immune response. DCs have a unique character of immunoregulation. DC-SIGN, a molecule designated as CD209, is one member of the C-type lectin superfamily. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. DC-SIGN has become hotspot of recent studies because of its important role in mediating DC adhesion, migration, inflammation, activating primary T cell, triggering immune response and participating in immune escape of pathogens and tumors. These studies on DC-SIGN involved in primary and secondary immune response and relevant mechanism will certainly provide us with a new method in treating and preventing certain diseases.

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Year:  2006        PMID： 16978536

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


  45 in total

1.  Lung infections and innate host defense.

Authors:  Ma Valdivia-Arenas; A Amer; Ln Henning; Md Wewers; Ls Schlesinger
Journal:  Drug Discov Today Dis Mech       Date:  2007

2.  Enterobacter sakazakii targets DC-SIGN to induce immunosuppressive responses in dendritic cells by modulating MAPKs.

Authors:  Rahul Mittal; Silvia Bulgheresi; Claudia Emami; Nemani V Prasadarao
Journal:  J Immunol       Date:  2009-10-21       Impact factor: 5.422

3.  Different potential of C-type lectin-mediated entry between Marburg virus strains.

Authors:  Keita Matsuno; Noriko Kishida; Katsuaki Usami; Manabu Igarashi; Reiko Yoshida; Eri Nakayama; Masayuki Shimojima; Heinz Feldmann; Tatsuro Irimura; Yoshihiro Kawaoka; Ayato Takada
Journal:  J Virol       Date:  2010-03-10       Impact factor: 5.103

4.  Comparative analysis of microbial sensing molecules in mucosal tissues with aging.

Authors:  O A Gonzalez; S Kirakodu; M J Novak; A J Stromberg; L Orraca; J Gonzalez-Martinez; A Burgos; J L Ebersole
Journal:  Immunobiology       Date:  2017-10-16       Impact factor: 3.144

5.  Vaccines delivered by integration-deficient lentiviral vectors targeting dendritic cells induces strong antigen-specific immunity.

Authors:  Biliang Hu; Bingbing Dai; Pin Wang
Journal:  Vaccine       Date:  2010-08-13       Impact factor: 3.641

Review 6.  C-type lectins and phagocytosis.

Authors:  Ann M Kerrigan; Gordon D Brown
Journal:  Immunobiology       Date:  2009-03-03       Impact factor: 3.144

7.  Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.

Authors:  Tanja Zeller; Philipp Wild; Silke Szymczak; Maxime Rotival; Arne Schillert; Raphaele Castagne; Seraya Maouche; Marine Germain; Karl Lackner; Heidi Rossmann; Medea Eleftheriadis; Christoph R Sinning; Renate B Schnabel; Edith Lubos; Detlev Mennerich; Werner Rust; Claire Perret; Carole Proust; Viviane Nicaud; Joseph Loscalzo; Norbert Hübner; David Tregouet; Thomas Münzel; Andreas Ziegler; Laurence Tiret; Stefan Blankenberg; François Cambien
Journal:  PLoS One       Date:  2010-05-18       Impact factor: 3.240

8.  Engineered lentivector targeting of dendritic cells for in vivo immunization.

Authors:  Lili Yang; Haiguang Yang; Kendra Rideout; Taehoon Cho; Kye Il Joo; Leslie Ziegler; Abigail Elliot; Anthony Walls; Dongzi Yu; David Baltimore; Pin Wang
Journal:  Nat Biotechnol       Date:  2008-02-24       Impact factor: 54.908

9.  Association of CD209 and CD209L polymorphisms with tuberculosis infection in a Northeastern Brazilian population.

Authors:  Ronaldo Celerino da Silva; Ludovica Segat; Heidi Lacerda Alves da Cruz; Haiana Charifker Schindler; Lilian Maria Lapa Montenegro; Sergio Crovella; Rafael Lima Guimarães
Journal:  Mol Biol Rep       Date:  2014-05-30       Impact factor: 2.316

10.  The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses.

Authors:  Karin Fredriksson; Amarjit Mishra; Jonathan K Lam; Elizabeth M Mushaben; Rosemarie A Cuento; Katharine S Meyer; Xianglan Yao; Karen J Keeran; Gayle Z Nugent; Xuan Qu; Zu-Xi Yu; Yanqin Yang; Nalini Raghavachari; Pradeep K Dagur; J Philip McCoy; Stewart J Levine
Journal:  J Immunol       Date:  2014-04-14       Impact factor: 5.422
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