Literature DB >> 16978184

A high-resolution comparative radiation hybrid map of equine chromosome 4q12-q22.

C Dierks1, S Mömke, C Drögemüller, T Leeb, B P Chowdhary, O Distl.   

Abstract

In this study, we present a comprehensive 5000-rad radiation hybrid map of a 40-cM region on equine chromosome 4 (ECA4) that contains quantitative trait loci for equine osteochondrosis. We mapped 29 gene-associated sequence tagged site markers using primers designed from equine expressed sequence tags or BAC clones in the ECA4q12-q22 region. Three blocks of conserved synteny, showing two chromosomal breakpoints, were identified in the segment of ECA4q12-q22. Markers from other segments of HSA7q mapped to ECA13p and ECA4p, and a region of HSA7p was homologous to ECA13p. Therefore, we have improved the resolution of the human-equine comparative map, which allows the identification of candidate genes underlying traits of interest.

Entities:  

Mesh：

Year:  2006        PMID： 16978184     DOI： 10.1111/j.1365-2052.2006.01510.x

Source DB:  PubMed          Journal:  Anim Genet        ISSN： 0268-9146            Impact factor:   3.169


  5 in total

1.  Exploration of Potential Ewing Sarcoma Drugs from FDA-Approved Pharmaceuticals through Computational Drug Repositioning, Pharmacogenomics, Molecular Docking, and MD Simulation Studies.

Authors:  Mubashir Hassan; Muhammad Yasir; Saba Shahzadi; Andrzej Kloczkowski
Journal:  ACS Omega       Date:  2022-06-01

Review 2.  The horse genome derby: racing from map to whole genome sequence.

Authors:  Bhanu P Chowdhary; Terje Raudsepp
Journal:  Chromosome Res       Date:  2008       Impact factor: 5.239

3.  A 4,103 marker integrated physical and comparative map of the horse genome.

Authors:  T Raudsepp; A Gustafson-Seabury; K Durkin; M L Wagner; G Goh; C M Seabury; C Brinkmeyer-Langford; E-J Lee; R Agarwala; E Stallknecht-Rice; A A Schäffer; L C Skow; T Tozaki; H Yasue; M C T Penedo; L A Lyons; K A Khazanehdari; M M Binns; J N MacLeod; O Distl; G Guérin; T Leeb; J R Mickelson; B P Chowdhary
Journal:  Cytogenet Genome Res       Date:  2008-10-14       Impact factor: 1.636

4.  Genome-wide search for markers associated with osteochondrosis in Hanoverian warmblood horses.

Authors:  Claudia Dierks; Kathrin Löhring; Virginie Lampe; Catherine Wittwer; Cord Drögemüller; Ottmar Distl
Journal:  Mamm Genome       Date:  2007-09-29       Impact factor: 2.957

5.  Genetic diversity and population structure of Mongolian regional horses with 14 microsatellite markers.

Authors:  Jihye Yun; Baatartsogt Oyungerel; Hong Sik Kong
Journal:  Anim Biosci       Date:  2022-03-02
  5 in total

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