Literature DB >> 169751

Nitrosyl-hemoglobin formation in the blood of animals exposed to nitric oxide.

H Oda, S Kusumoto, T Nakajima.   

Abstract

Animals were exposed to nitric oxide (NO) in order to study its biological effect. First a method was developed to exclude nitrogen dioxide formed during exposure of NO. Nitrosyl-hemoglobin (NOHb) in the blood of mice, rats, and rabbits exposed to NO was determined by electron spin resonance spectrometry at -100C. The content of NOHb in the blood of the mouse reached the maximum (0.13% of the total hemoglobin) 20 minutes after the exposure was begun and thereafter a state of equilibrium was maintained. The NOHv level decreased to one half in several minutes after the mouse was removed to a filtered air environment. Dose-response relationship was observed between gas concentrations and the maximum NOHb level.

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Year:  1975        PMID： 169751     DOI： 10.1080/00039896.1975.10666749

Source DB:  PubMed          Journal:  Arch Environ Health        ISSN： 0003-9896


  16 in total

1.  Bronchodilator action of inhaled nitric oxide in guinea pigs.

Authors:  P M Dupuy; S A Shore; J M Drazen; C Frostell; W A Hill; W M Zapol
Journal:  J Clin Invest       Date:  1992-08       Impact factor: 14.808

2.  Successful use of inhaled nitric oxide for severe hypoxemia in an infant with acute exacerbation of bronchiolitis due to sepsis.

Authors:  K Okamoto; T Tashima; I Kukita; T Sato; M Kurose; K Taki
Journal:  J Anesth       Date:  1995-03       Impact factor: 2.078

3.  Nitrosylhemoglobin and carboxyhemoglobin in the blood of mice simultaneously exposed to nitric oxide and carbon monoxide.

Authors:  H Oda; H Nogami; S Kusumoto; T Nakajima
Journal:  Bull Environ Contam Toxicol       Date:  1976-11       Impact factor: 2.151

Review 4.  Inhaled vasodilator therapy in acute lung injury: first, do NO harm?

Authors:  S J Brett; T W Evans
Journal:  Thorax       Date:  1995-08       Impact factor: 9.139

5.  Continuous inhalation of nitric oxide protects against development of pulmonary hypertension in chronically hypoxic rats.

Authors:  C Kouyoumdjian; S Adnot; M Levame; S Eddahibi; H Bousbaa; B Raffestin
Journal:  J Clin Invest       Date:  1994-08       Impact factor: 14.808

6.  Effect of exposure to 43 ppm nitric oxide and 3.6 ppm nitrogen dioxide on rabbit lung. A light and electron microscopic study.

Authors:  C Hugod
Journal:  Int Arch Occup Environ Health       Date:  1979-01-15       Impact factor: 3.015

7.  Metabolic fate of nitric oxide.

Authors:  K Yoshida; K Kasama; M Kitabatake; M Okuda; M Imai
Journal:  Int Arch Occup Environ Health       Date:  1980       Impact factor: 3.015

8.  Evaluation of Mapleson systems for administration of inhaled nitric oxide.

Authors:  I Kukita; K Okamoto; T Sato; Y Shibata; K Shiihara; K Kikuta
Journal:  J Anesth       Date:  1996-03       Impact factor: 2.078

9.  Brief periods of nitric oxide inhalation protect against myocardial ischemia-reperfusion injury.

Authors:  Yasuko Nagasaka; Bernadette O Fernandez; Maria F Garcia-Saura; Bodil Petersen; Fumito Ichinose; Kenneth D Bloch; Martin Feelisch; Warren M Zapol
Journal:  Anesthesiology       Date:  2008-10       Impact factor: 7.892

Review 10.  Nitric oxide, a biological effector. Electron paramagnetic resonance detection of nitrosyl-iron-protein complexes in whole cells.

Authors:  Y Henry; C Ducrocq; J C Drapier; D Servent; C Pellat; A Guissani
Journal:  Eur Biophys J       Date:  1991       Impact factor: 1.733
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