Literature DB >> 1697210

Ethanol enhancement of GABA-activated chloride current in rat dorsal root ganglion neurons.

M Nishio1, T Narahashi.   

Abstract

The acute effects of ethanol on the gamma-aminobutyric acid (GABA)-activated current were studied with the rat dorsal root ganglion neurons in primary culture using the whole-cell patch-clamp technique. GABA produced an inward chloride current, which was composed of an initial transient and a subsequent sustained phase. Ethanol at concentrations ranging from 30 to 300 mM enhanced the transient current in a concentration-dependent manner without affecting the sustained current.

Entities:  

Mesh:

Substances:

Year:  1990        PMID: 1697210     DOI: 10.1016/0006-8993(90)90982-h

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  6 in total

Review 1.  GABA(A) receptors and alcohol.

Authors:  Ingrid A Lobo; R Adron Harris
Journal:  Pharmacol Biochem Behav       Date:  2008-03-14       Impact factor: 3.533

2.  Anisatin modulation of the gamma-aminobutyric acid receptor-channel in rat dorsal root ganglion neurons.

Authors:  T Ikeda; Y Ozoe; E Okuyama; K Nagata; H Honda; T Shono; T Narahashi
Journal:  Br J Pharmacol       Date:  1999-08       Impact factor: 8.739

3.  Alpha6-containing nicotinic acetylcholine receptor is a highly sensitive target of alcohol.

Authors:  Fenfei Gao; Dejie Chen; Xiaokuang Ma; Sterling Sudweeks; Jordan T Yorgason; Ming Gao; Dharshaun Turner; Jason Brek Eaton; J Michael McIntosh; Ronald J Lukas; Paul Whiteaker; Yongchang Chang; Scott C Steffensen; Jie Wu
Journal:  Neuropharmacology       Date:  2019-01-30       Impact factor: 5.250

4.  Prenatal Exposure to Ethanol Alters Synaptic Activity in Layer V/VI Pyramidal Neurons of the Somatosensory Cortex.

Authors:  Laurie C Delatour; Pamela W L Yeh; Hermes H Yeh
Journal:  Cereb Cortex       Date:  2020-03-14       Impact factor: 5.357

Review 5.  Synaptic effects induced by alcohol.

Authors:  David M Lovinger; Marisa Roberto
Journal:  Curr Top Behav Neurosci       Date:  2013

6.  Acute effects of ethanol on GABAA and glycine currents in the lateral habenula neurons of young rats.

Authors:  Zijing Xie; Guohui Li; Jiang-Hong Ye
Journal:  Open J Neurosci       Date:  2013-08-21
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.