Literature DB >> 16967588

[Coma in a child after treatment with the 'magic salve' lidocaine-prilocaine cream].

J W Wieringa1, A G Ketel, M A van Houten.   

Abstract

A 2-year-old girl lost consciousness after the topical application of lidocaine-prilocaine cream (EMLA) in preparation for the removal of multiple mollusca contagiosa. Both the area on which cream was applied (80% of body surface) and the total amount of cream (90 g) exceeded the maximum dosage. Lidocaine-prilocaine cream is a widely used local anaesthetic with few side effects when used properly. Intoxication with a lidocaine-prilocaine preparation may have serious consequences, such as changes in intracardiac conduction, excitation or depression of the central nervous system and methaemoglobinaemia. In our patient both methaemoglobinaemia and depression of the central nervous system occurred, resulting in loss of consciousness. She was treated with 100% oxygen and fully recovered.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16967588

Source DB:  PubMed          Journal:  Ned Tijdschr Geneeskd        ISSN: 0028-2162


  2 in total

Review 1.  Interventions for cutaneous molluscum contagiosum.

Authors:  Johannes C van der Wouden; Renske van der Sande; Emma J Kruithof; Annet Sollie; Lisette Wa van Suijlekom-Smit; Sander Koning
Journal:  Cochrane Database Syst Rev       Date:  2017-05-17

2.  [Methemoglobin intoxication by prilocaine in EMLA. Accidental intoxication of an infant with scald injuries].

Authors:  A Book; C Fehlandt; M Krija; M Radke; D Pappert
Journal:  Anaesthesist       Date:  2009-04       Impact factor: 1.041

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.