Literature DB >> 16966854

Normothermic bypass in pediatric surgery: technical aspect and clinical experience with 1400 cases.

Yves D Durandy1, Sylvie H Hulin.   

Abstract

We analyzed our experience with warm perfusion and blood cardioplegia in pediatric surgery. Warm surgery was performed in 1400 patients. Prime and perfusate are kept at 37 degrees C before and during bypass and intermittent warm blood cardioplegia is used for myocardial protection. Analyzed parameters were: perioperative blood gas, hydric balance of cardioplegia, spontaneous resumption of rhythm after aortic unclamping, troponin I level, postoperative neurologic and renal function, duration of mechanical ventilation (five diagnostic groups), and duration of intensive care unit (ICU) stay. Satisfactory gas exchange is the rule, and fluid addition is negligible during warm cardioplegia. Spontaneous resumption of sinus rhythm occurred in 99% of patients, Troponin I elevation was < 10 ng/ml in 46% of cases. Prevalence of neurologic complications (0.3%) and of renal insufficiency treated by peritoneal dialysis (0.35%) favorably compares with data reported in the literature. Average mechanical ventilation time was < 48 hours in each diagnostic group. Duration of ICU stay was < 48 hours in 86% of the 1400 patients. In our experience, normothermic surgery is an excellent alternative to hypothermia.

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Year:  2006        PMID: 16966854     DOI: 10.1097/01.mat.0000242597.92625.e9

Source DB:  PubMed          Journal:  ASAIO J        ISSN: 1058-2916            Impact factor:   2.872


  9 in total

1.  International conference on pediatric mechanical circulatory support systems and pediatric cardiopulmonary perfusion: outcomes and future directions.

Authors:  Akif Undar
Journal:  ASAIO J       Date:  2008 Mar-Apr       Impact factor: 2.872

Review 2.  Blood Versus Crystalloid Cardioplegia in Pediatric Cardiac Surgery: A Systematic Review and Meta-analysis.

Authors:  Konstantinos S Mylonas; Aspasia Tzani; Panagiotis Metaxas; Dimitrios Schizas; Vasileios Boikou; Konstantinos P Economopoulos
Journal:  Pediatr Cardiol       Date:  2017-09-25       Impact factor: 1.655

3.  Perfusionist strategies for blood conservation in pediatric cardiac surgery.

Authors:  Yves Durandy
Journal:  World J Cardiol       Date:  2010-02-26

4.  Cardioprotection of neonatal heart using normothermic hyperkalaemia: the importance of delivery and terminal cardioplegia.

Authors:  Hajime Imura; M-Saadeh Suleiman
Journal:  Mol Cell Biochem       Date:  2007-11-25       Impact factor: 3.396

Review 5.  Normothermia for pediatric and congenital heart surgery: an expanded horizon.

Authors:  Ahmad Mahir Shamsuddin; Ahmad Mohd Nikman; Saedah Ali; Mohd Rizal Mohd Zain; Abdul Rahim Wong; Antonio Francesco Corno
Journal:  Front Pediatr       Date:  2015-04-28       Impact factor: 3.418

6.  Normothermic versus hypothermic cardiopulmonary bypass in children undergoing open heart surgery (thermic-2): study protocol for a randomized controlled trial.

Authors:  Sarah Baos; Karen Sheehan; Lucy Culliford; Katie Pike; Lucy Ellis; Andrew J Parry; Serban Stoica; Mohamed T Ghorbel; Massimo Caputo; Chris A Rogers
Journal:  JMIR Res Protoc       Date:  2015-05-25

7.  Comparison of Early Outcomes for Normothermic and Hypothermic Cardiopulmonary Bypass in Children Undergoing Congenital Heart Surgery.

Authors:  Antonio F Corno; Claire Bostock; Simon D Chiles; Joanna Wright; Maria-Teresa Jn Tala; Branko Mimic; Mirjana Cvetkovic
Journal:  Front Pediatr       Date:  2018-08-17       Impact factor: 3.418

8.  Safety of Normothermic Cardiopulmonary Bypass in Pediatric Cardiac Surgery: A System Review and Meta-Analysis.

Authors:  Tao Xiong; Lei Pu; Yuan-Feng Ma; Yun-Long Zhu; Xu Cui; Hua Li; Xu Zhan; Ya-Xiong Li
Journal:  Front Pediatr       Date:  2021-12-14       Impact factor: 3.418

9.  Part II. Comparison of Neurodevelopmental Outcomes Between Normothermic and Hypothermic Pediatric Cardiopulmonary Bypass.

Authors:  Claire E Hannon; Zachary Osman; Cathy Grant; Emma M L Chung; Antonio F Corno
Journal:  Front Pediatr       Date:  2019-11-05       Impact factor: 3.418

  9 in total

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