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Literature DB >> 16966697

Another important function for an old friend! The role of iron in colorectal carcinogenesis.

J R Butterworth¹.

Abstract

Entities: Chemical Disease

Mesh：

Substances：

Year: 2006 PMID： 16966697 PMCID： PMC1856437 DOI： 10.1136/gut.2006.098350

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

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35 in total

1. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.

Authors: A Cano; M A Pérez-Moreno; I Rodrigo; A Locascio; M J Blanco; M G del Barrio; F Portillo; M A Nieto
Journal: Nat Cell Biol Date: 2000-02 Impact factor: 28.824

2. Modulation of iron transport proteins in human colorectal carcinogenesis.

Authors: M J Brookes; S Hughes; F E Turner; G Reynolds; N Sharma; T Ismail; G Berx; A T McKie; N Hotchin; G J Anderson; T Iqbal; C Tselepis
Journal: Gut Date: 2006-04-26 Impact factor: 23.059

3. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: The mechanisms involved in inhibiting cell-cycle progression.

Authors: J Gao; D R Richardson
Journal: Blood Date: 2001-08-01 Impact factor: 22.113

4. Chronic exposure to high levels of dietary iron fortification increases lipid peroxidation in the mucosa of the rat large intestine.

Authors: E K Lund; S J Fairweather-Tait; S G Wharf; I T Johnson
Journal: J Nutr Date: 2001-11 Impact factor: 4.798

5. Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines.

Authors: N Rakba; P Loyer; D Gilot; J G Delcros; D Glaise; P Baret; J L Pierre; P Brissot; G Lescoat
Journal: Carcinogenesis Date: 2000-05 Impact factor: 4.944

6. Cdx1 and cdx2 expression during intestinal development.

Authors: D G Silberg; G P Swain; E R Suh; P G Traber
Journal: Gastroenterology Date: 2000-10 Impact factor: 22.682

7. Iron chelators inhibit the growth and induce the apoptosis of Kaposi's sarcoma cells and of their putative endothelial precursors.

Authors: T Simonart; C Degraef; G Andrei; R Mosselmans; P Hermans; J P Van Vooren; J C Noel; J R Boelaert; R Snoeck; M Heenen
Journal: J Invest Dermatol Date: 2000-11 Impact factor: 8.551

Another important function for an old friend! The role of iron in colorectal carcinogenesis.

1. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.

2. Modulation of iron transport proteins in human colorectal carcinogenesis.

3. The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: The mechanisms involved in inhibiting cell-cycle progression.

4. Chronic exposure to high levels of dietary iron fortification increases lipid peroxidation in the mucosa of the rat large intestine.

5. Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines.

6. Cdx1 and cdx2 expression during intestinal development.

7. Iron chelators inhibit the growth and induce the apoptosis of Kaposi's sarcoma cells and of their putative endothelial precursors.

8. Heme iron, zinc, alcohol consumption, and colon cancer: Iowa Women's Health Study.

9. Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer.

10. c-Myc represses the murine Nramp1 promoter.

1. Presence of iron in colorectal adenomas and adenocarcinomas.

2. Gender and plasma iron biomarkers, but not HFE gene mutations, increase the risk of colorectal cancer and polyps.

3. Interrelationships between circulating gastrin and iron status in mice and humans.