| Literature DB >> 16965818 |
José S Casas1, Eduardo E Castellano, María D Couce, Javier Ellena, Agustín Sánchez, José Sordo, Carmen Taboada.
Abstract
Reaction of the vitamin K(3) derivative menadione sodium bisulfite thiosemicarbazone (NaK(3)TSC) with chloro(triethylphosphine)gold(I) afforded the complex [AuPEt(3)(K(3)TSC)]. This compound consists of discrete molecules in which the metal is almost linearly coordinated to P and S. Preliminary in vitro screening showed significant anti-cancer activity, notably against the cisplatin-resistant cell line A2780cis.Entities:
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Year: 2006 PMID： 16965818 DOI： 10.1016/j.jinorgbio.2006.07.006
Source DB: PubMed Journal: J Inorg Biochem ISSN： 0162-0134 Impact factor: 4.155