Literature DB >> 16965137

Porcine skin visible lesion thresholds for near-infrared lasers including modeling at two pulse durations and spot sizes.

C P Cain1, G D Polhamus, W P Roach, D J Stolarski, K J Schuster, K L Stockton, B A Rockwell, Bo Chen, A J Welch.   

Abstract

With the advent of such systems as the airborne laser and advanced tactical laser, high-energy lasers that use 1315-nm wavelengths in the near-infrared band will soon present a new laser safety challenge to armed forces and civilian populations. Experiments in nonhuman primates using this wavelength have demonstrated a range of ocular injuries, including corneal, lenticular, and retinal lesions as a function of pulse duration. American National Standards Institute (ANSI) laser safety standards have traditionally been based on experimental data, and there is scant data for this wavelength. We are reporting minimum visible lesion (MVL) threshold measurements using a porcine skin model for two different pulse durations and spot sizes for this wavelength. We also compare our measurements to results from our model based on the heat transfer equation and rate process equation, together with actual temperature measurements on the skin surface using a high-speed infrared camera. Our MVL-ED50 thresholds for long pulses (350 micros) at 24-h postexposure are measured to be 99 and 83 J cm(-2) for spot sizes of 0.7 and 1.3 mm diam, respectively. Q-switched laser pulses of 50 ns have a lower threshold of 11 J cm(-2) for a 5-mm-diam top-hat laser pulse.

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Year:  2006        PMID: 16965137     DOI: 10.1117/1.2338815

Source DB:  PubMed          Journal:  J Biomed Opt        ISSN: 1083-3668            Impact factor:   3.170


  5 in total

1.  Development of compression-controlled low-level laser probe system: towards clinical application.

Authors:  Changmin Yeo; Taeyoon Son; Junghwan Park; Young-Heum Lee; Kiwoon Kwon; J Stuart Nelson; Byungjo Jung
Journal:  Lasers Med Sci       Date:  2010-09       Impact factor: 3.161

2.  Picosecond Laser-Induced Photothermal Skin Damage Evaluation by Computational Clinical Trial.

Authors:  Y Shimojo; T Nishimura; H Hazama; N Ito; K Awazu
Journal:  Laser Ther       Date:  2020-07-17

3.  Thermal damage thresholds for multiple-pulse porcine skin laser exposures at 1070 nm.

Authors:  Michael P DeLisi; Morgan S Schmidt; Aaron F Hoffman; Amanda M Peterson; Gary D Noojin; Aurora D Shingledecker; Adam R Boretsky; David J Stolarski; Semih S Kumru; Robert J Thomas
Journal:  J Biomed Opt       Date:  2019-09       Impact factor: 3.170

4.  Porcine skin damage thresholds and histological damage characteristics from 1319-nm laser radiation.

Authors:  Luguang Jiao; Jiarui Wang; Yan Fan; Zaifu Yang
Journal:  J Biomed Opt       Date:  2019-09       Impact factor: 3.170

5.  Acute exposure of 532 nm laser differentially regulates skin tissue transcription factors.

Authors:  Rajkumar Tulsawani; Purva Sharma; Niroj Kumar Sethy; Pooja Kumari; Lilly Ganju; Satya Prakash; Satish Chouhan
Journal:  PLoS One       Date:  2020-03-19       Impact factor: 3.240

  5 in total

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