| Literature DB >> 16965124 |
Jason Hirshburg, Bernard Choi, J Stuart Nelson, Alvin T Yeh.
Abstract
Biomedical optics and photomedicine applications are challenged by the turbidity of most biological tissue systems. Nonreactive, biocompatible chemical agents can induce a reversible reduction in optical scattering of collagenous tissues such as human skin. Herein we show that a chemical agent's tissue optical clearing potential is directly related to its collagen solubility, providing a rational design basis for effective, percutaneous formulations.Entities:
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Year: 2006 PMID: 16965124 DOI: 10.1117/1.2220527
Source DB: PubMed Journal: J Biomed Opt ISSN: 1083-3668 Impact factor: 3.170