SETTING: Six provinces in Vietnam where the DOTS strategy was introduced in 1989. OBJECTIVE: To assess the impact of improved tuberculosis (TB) control on TB epidemiology in Vietnam. METHODS: Data from the surveillance system in the period 1990-2003 were analysed to assess trends of notification rates and the mean ages of notified cases. Data from repeated tuberculin surveys in the period 1986-2002 were estimated to assess the prevalence of TB infection, the annual risk of infection and its trend using various cut-off points in those with and without bacille Calmette-Guérin (BCG) scar. RESULTS: Age-standardised notification rates in the period 1996-2003 declined significantly, by 2.6% to 5.9% per year, in five provinces. However, in four provinces notification rates in the age group 15-24 years increased significantly, by 4.5% to 13.6% per year, during this period. The mean age of newly diagnosed patients with smear-positive TB increased up to 1995 but decreased thereafter. The annual risk of TB infection showed a significant annual decrease (4.9% per year) in one province in surveys performed between 1986 and 1997, and in two provinces (6.6% and 4.7%) in surveys conducted between 1993 and 2002. CONCLUSION: These data suggest limited impact to date of the DOTS strategy in Vietnam.
SETTING: Six provinces in Vietnam where the DOTS strategy was introduced in 1989. OBJECTIVE: To assess the impact of improved tuberculosis (TB) control on TB epidemiology in Vietnam. METHODS: Data from the surveillance system in the period 1990-2003 were analysed to assess trends of notification rates and the mean ages of notified cases. Data from repeated tuberculin surveys in the period 1986-2002 were estimated to assess the prevalence of TB infection, the annual risk of infection and its trend using various cut-off points in those with and without bacille Calmette-Guérin (BCG) scar. RESULTS: Age-standardised notification rates in the period 1996-2003 declined significantly, by 2.6% to 5.9% per year, in five provinces. However, in four provinces notification rates in the age group 15-24 years increased significantly, by 4.5% to 13.6% per year, during this period. The mean age of newly diagnosed patients with smear-positive TB increased up to 1995 but decreased thereafter. The annual risk of TB infection showed a significant annual decrease (4.9% per year) in one province in surveys performed between 1986 and 1997, and in two provinces (6.6% and 4.7%) in surveys conducted between 1993 and 2002. CONCLUSION: These data suggest limited impact to date of the DOTS strategy in Vietnam.
Authors: Sean P Fitzwater; Luz Caviedes; Robert H Gilman; Jorge Coronel; Doris LaChira; Cayo Salazar; Juan Carlos Saravia; Krishna Reddy; Jon S Friedland; David A J Moore Journal: Clin Infect Dis Date: 2010-08-15 Impact factor: 9.079
Authors: Ngoc Buu Tran; Rein M G J Houben; Thi Quy Hoang; Thi Ngoc Lan Nguyen; Martien W Borgdorff; Frank G J Cobelens Journal: Emerg Infect Dis Date: 2007-10 Impact factor: 6.883
Authors: Tran N Buu; Mai N T Huyen; Nguyen N T Lan; Hoang T Quy; Nguyen V Hen; Matteo Zignol; Martien W Borgdorff; Dick van Soolingen; Frank G J Cobelens Journal: Emerg Infect Dis Date: 2009-10 Impact factor: 6.883
Authors: E L Corbett; T Bandason; Y-B Cheung; B Makamure; E Dauya; S S Munyati; G J Churchyard; B G Williams; A E Butterworth; S Mungofa; R J Hayes; P R Mason Journal: Int J Tuberc Lung Dis Date: 2009-10 Impact factor: 2.373