Literature DB >> 16964438

Ameliorating role of caffeic acid phenethyl ester (CAPE) against isoniazid-induced oxidative damage in red blood cells.

Osman Gokalp1, Efkan Uz, Ekrem Cicek, H Ramazan Yilmaz, Mehmet Kaya Ozer, Ayse Altunbas, Nurten Ozcelik.   

Abstract

Isoniazid (INH) still remains a first-line drug both for treatment and prophylaxis of tuberculosis, but various organs toxicity frequently develops in patients receiving this drug. We aimed to investigate possible toxic effects of INH on rat red blood cells (RBCs), and to elucidate whether Caffeic acid phenethyl ester (CAPE) prevents a possible toxic effect of INH. Experimental groups were designed as follows: control group, INH group, INH + CAPE group. Compared with the control, the INH caused a significant increase in superoxide dismutase (SOD) activity and malondialdehyde (MDA) levels, and a decrease in glutathione peroxidase (GSH-Px) and catalase (CAT), which are recently used to monitor the development and extent of damage due to oxidative stresses. CAPE administration to INH group ameliorated above changes due to INH.

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Year:  2006        PMID： 16964438     DOI： 10.1007/s11010-006-9157-z

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  30 in total

1.  Study of oxidative-stress in isoniazid-rifampicin induced hepatic injury in young rats.

Authors:  C P Sodhi; S V Rana; S K Mehta; K Vaiphei; S Attari; S Mehta
Journal:  Drug Chem Toxicol       Date:  1997-08       Impact factor: 3.356

2.  Isoniazid- and rifampicin-induced oxidative hepatic injury--protection by N-acetylcysteine.

Authors:  S Attri; S V Rana; K Vaiphei; C P Sodhi; R Katyal; R C Goel; C K Nain; K Singh
Journal:  Hum Exp Toxicol       Date:  2000-09       Impact factor: 2.903

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Journal:  Postgrad Med J       Date:  1987-04       Impact factor: 2.401

4.  A simple method for clinical assay of superoxide dismutase.

Authors:  Y Sun; L W Oberley; Y Li
Journal:  Clin Chem       Date:  1988-03       Impact factor: 8.327

Review 5.  Role of free radicals in toxic hepatic injury. I. Free radical biochemistry.

Authors:  J A Brent; B H Rumack
Journal:  J Toxicol Clin Toxicol       Date:  1993

6.  Heterogeneity of erythrocyte catalase II. Isolation and characterization of normal and variant erythrocyte catalase and their subunits.

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Journal:  Eur J Biochem       Date:  1974-10-01

7.  Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase.

Authors:  D E Paglia; W N Valentine
Journal:  J Lab Clin Med       Date:  1967-07

Review 8.  Variations between individuals and populations in the acetylation of isoniazid and its significance for the treatment of pulmonary tuberculosis.

Authors:  G A Ellard
Journal:  Clin Pharmacol Ther       Date:  1976-05       Impact factor: 6.875

9.  Topically applied water extract of propolis to suppress corneal neovascularization in rabbits.

Authors:  I F Hepşen; H Er; O Cekiç
Journal:  Ophthalmic Res       Date:  1999       Impact factor: 2.892

10.  Oxidative-hepatic injury of isoniazid-rifampicin in young rats subjected to protein and energy malnutrition.

Authors:  C P Sodhi; S F Rana; S Attri; S Mehta; K Yaiphei; S K Mehta
Journal:  Drug Chem Toxicol       Date:  1998-08       Impact factor: 3.356
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  4 in total

1.  Effect of caffeic acid phenethyl ester on myringosclerosis development in the tympanic membrane of rat.

Authors:  Vefa Kinis; Musa Ozbay; Ulas Alabalik; Aylin Gul; Beyhan Yilmaz; Fazi Emre Ozkurt; Engin Sengul; Ismail Topcu
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-11-27       Impact factor: 2.503

2.  Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes.

Authors:  Luc H Boudreau; Jacques Maillet; Luc M LeBlanc; Jacques Jean-François; Mohamed Touaibia; Nicolas Flamand; Marc E Surette
Journal:  PLoS One       Date:  2012-02-09       Impact factor: 3.240

3.  Preventative effects of caffeic Acid phenyl ester on cadmium intoxication induced hematological and blood coagulation disturbances and hepatorenal damage in rats.

Authors:  Tariq Helal Ashour
Journal:  ISRN Hematol       Date:  2014-03-30

4.  Probing the in vitro cytotoxicity of the veterinary drug oxytetracycline.

Authors:  Zhenxing Chi; Rutao Liu; Hong You; Shanshan Ma; Hao Cui; Qiang Zhang
Journal:  PLoS One       Date:  2014-07-14       Impact factor: 3.240
  4 in total

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