| Literature DB >> 16963391 |
Birte Friedrichs, Markus Tiemann, Hans Salwender, Karl Verpoort, Michael K Wenger, Norbert Schmitz.
Abstract
A 35-year old woman developed Burkitt's lymphoma and was treated with rituximab and CHOP therapy early during pregnancy. Monitoring of rituximab concentrations and B-cell counts in the child revealed a transient complete B-cell depletion associated with high rituximab cord blood concentrations. B-cell recovery was fast, showing a regular immunophenotype without loss of CD20 antigen, no functional deficits and adequate vaccination IgG titers.Entities:
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Year: 2006 PMID: 16963391
Source DB: PubMed Journal: Haematologica ISSN: 0390-6078 Impact factor: 9.941